| Literature DB >> 12943426 |
Benjamin R Graetz1, Scott D Rychnovsky.
Abstract
[reaction: see text] A formal synthesis of (-)-apicularen A has been completed. The synthesis features a cyanohydrin acetonide coupling as a convergent approach to the C9-C18 segment and an intramolecular Diels-Alder addition sequence to create both the 10-membered macrocycle and the aromatic ring.Entities:
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Year: 2003 PMID： 12943426 DOI： 10.1021/ol0353417
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005