Literature DB >> 12943413

Use of bis-(chiral alpha-methylbenzyl)glycine esters for synthesis of enantiopure beta-hydroxyamino esters.

Ayako Yamashita1, Emily B Norton, R Thomas Williamson, Douglas M Ho, Sandra Sinishtaj, Tarek S Mansour.   

Abstract

[reaction: see text] Aldol reactions using bis-(chiral alpha-methylbenzyl)glycine esters with aldehydes gave excellent diastereoselectivity. Thus, an enantiopure ribosylglycine was prepared for the synthesis of analogues of the natural antibiotics muraymycin. This method was extended for formation of beta-hydroxyamino esters.

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Year:  2003        PMID: 12943413     DOI: 10.1021/ol030085j

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Stereocontrolled Total Synthesis of Muraymycin D1 Having a Dual Mode of Action against Mycobacterium tuberculosis.

Authors:  Katsuhiko Mitachi; Bilal A Aleiwi; Christopher M Schneider; Shajila Siricilla; Michio Kurosu
Journal:  J Am Chem Soc       Date:  2016-09-26       Impact factor: 15.419

2.  A Unified Approach to Phytosiderophore Natural Products.

Authors:  Nicolas Kratena; Tobias Gökler; Lara Maltrovsky; Eva Oburger; Christian Stanetty
Journal:  Chemistry       Date:  2020-10-28       Impact factor: 5.020

  2 in total

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