Literature DB >> 12943403

R3Al-R'3SiOTf: novel and powerful reagent system for stereospecific alkylation-silylation reactions of epoxides.

Ponnusamy Shanmugam1, Masaaki Miyashita.   

Abstract

[reaction: see text] A novel and powerful reagent system R(3)Al-R'(3)SiOTf for the one-pot alkylation-silylation reaction of epoxides was discovered, and the reactions of various epoxides with the new reagent system have been demonstrated to occur stereospecifically giving rise to the corresponding alkylation-silylation products in excellent yields.

Entities:  

Year:  2003        PMID： 12943403     DOI： 10.1021/ol035075x

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Efficient synthesis of the C(7)-C(20) subunit of amphidinolides C and F.

Authors:  Subham Mahapatra; Rich G Carter
Journal:  Org Biomol Chem       Date:  2009-09-16       Impact factor: 3.876

2.  Carbocyclic 4'-Epiformycin.

Authors:  Jian Zhou; Minmin Yang; Akin Akdag; Haisheng Wang; Stewart W Schneller
Journal:  Tetrahedron       Date:  2008-01-07       Impact factor: 2.457

3.  Regioselective Cleavage of 3,4-Epoxy Alcohols with Substituted Alkynylaluminum Reagents: Application to the Stereoselective Synthesis of Polypropionates.

Authors:  Wilnelia Dávila; Wildeliz Torres; José A Prieto
Journal:  Tetrahedron       Date:  2007-08-20       Impact factor: 2.457

4.  Exploiting hidden symmetry in natural products: total syntheses of amphidinolides C and F.

Authors:  Subham Mahapatra; Rich G Carter
Journal:  J Am Chem Soc       Date:  2013-07-11       Impact factor: 15.419
  4 in total

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