Literature DB >> 12942083

Splitting the difference: the germline-somatic mutation debate on generating antibody diversity.

Arthur M Silverstein1.   

Abstract

In the debate about the mechanism for the generation of immunological diversity, the initial positions of both 'somaticists' and 'germliners' were diametrically opposed. Then, as data developed favoring first one and then the other side, concessions were made, until the final solution showed that each had been at least partially correct.

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Year:  2003        PMID: 12942083     DOI: 10.1038/ni0903-829

Source DB:  PubMed          Journal:  Nat Immunol        ISSN: 1529-2908            Impact factor:   25.606


  3 in total

1.  Stems and standards: social interaction in the search for blood stem cells.

Authors:  Melinda Bonnie Fagan
Journal:  J Hist Biol       Date:  2010       Impact factor: 1.326

2.  Protein dynamics and the diversity of an antibody response.

Authors:  Ramkrishna Adhikary; Wayne Yu; Masayuki Oda; Jörg Zimmermann; Floyd E Romesberg
Journal:  J Biol Chem       Date:  2012-06-08       Impact factor: 5.157

3.  The antibody mining toolbox: an open source tool for the rapid analysis of antibody repertoires.

Authors:  Sara D'Angelo; Jacob Glanville; Fortunato Ferrara; Leslie Naranjo; Cheryl D Gleasner; Xiaohong Shen; Andrew R M Bradbury; Csaba Kiss
Journal:  MAbs       Date:  2014 Jan-Feb       Impact factor: 5.857

  3 in total

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