OBJECTIVES: To investigate the rates of latent TB infection (LTBI) in a sample of young people in San Diego County and examine potential predictors of a positive tuberculin skin test (TST). METHODS: Latino and foreign-born students from ten public middle and high schools were invited to screenings along with a random 10% sample of all other students. After obtaining parental consent, Mantoux tests were placed (N=2,698) and read (n=2,667 [98.9%]) in 48-72 hours. A positive TST was defined as > or =10 mm induration. The mean age of the sample was 14.34 years (SD=1.81); 50.1% were female (n=1,353); 78.5% were Latino (n=2,108); 35.7% were foreign-born (n=939); and 44.3% were uninsured (n=930). RESULTS: The positive TST rate for Latinos was 21.8% vs. 5.6% for non-Latinos, p<0.001. Foreign-born Latinos had the highest infection rate (31.3%), followed by foreign-born non-Latinos (20.4%), U.S.-born Latinos (15.4%), and U.S.-born non-Latinos (1.0%), p<0.001. Logistic regression was conducted to determine predictors of TST positivity. Being Latino (odds ratio [OR]=3.27), uninsured (OR=1.60), foreign-born (OR=3.90), and living in the south county region closest to the U.S./Mexico border (OR=2.72) were significant predictors. CONCLUSIONS: Results suggest that Latino youth near the California/Mexico border are at high risk for infection, for remaining undiagnosed, and for being under-treated for LTBI.
OBJECTIVES: To investigate the rates of latent TB infection (LTBI) in a sample of young people in San Diego County and examine potential predictors of a positive tuberculin skin test (TST). METHODS: Latino and foreign-born students from ten public middle and high schools were invited to screenings along with a random 10% sample of all other students. After obtaining parental consent, Mantoux tests were placed (N=2,698) and read (n=2,667 [98.9%]) in 48-72 hours. A positive TST was defined as > or =10 mm induration. The mean age of the sample was 14.34 years (SD=1.81); 50.1% were female (n=1,353); 78.5% were Latino (n=2,108); 35.7% were foreign-born (n=939); and 44.3% were uninsured (n=930). RESULTS: The positive TST rate for Latinos was 21.8% vs. 5.6% for non-Latinos, p<0.001. Foreign-born Latinos had the highest infection rate (31.3%), followed by foreign-born non-Latinos (20.4%), U.S.-born Latinos (15.4%), and U.S.-born non-Latinos (1.0%), p<0.001. Logistic regression was conducted to determine predictors of TST positivity. Being Latino (odds ratio [OR]=3.27), uninsured (OR=1.60), foreign-born (OR=3.90), and living in the south county region closest to the U.S./Mexico border (OR=2.72) were significant predictors. CONCLUSIONS: Results suggest that Latino youth near the California/Mexico border are at high risk for infection, for remaining undiagnosed, and for being under-treated for LTBI.
Authors: Mark L Wieland; Jennifer A Weis; Marilynn W Olney; Marty Alemán; Susan Sullivan; Kendra Millington; Connie O'Hara; Julie A Nigon; Irene G Sia Journal: Am J Public Health Date: 2011-07 Impact factor: 9.308
Authors: Mark L Wieland; Jonathan Nelson; Tiffany Palmer; Connie O'Hara; Jennifer A Weis; Julie A Nigon; Irene G Sia Journal: J Health Commun Date: 2012-12-13
Authors: Mark L Wieland; Jennifer A Weis; Barbara P Yawn; Susan M Sullivan; Kendra L Millington; Christina M Smith; Susan Bertram; Julie A Nigon; Irene G Sia Journal: J Immigr Minor Health Date: 2012-02
Authors: R S Garfein; R Lozada; L Liu; R Laniado-Laborin; T C Rodwell; R Deiss; J Alvelais; A Catanzaro; P G Chiles; S A Strathdee Journal: Int J Tuberc Lung Dis Date: 2009-05 Impact factor: 2.373
Authors: Melbourne F Hovell; Katharine E Schmitz; Elaine J Blumberg; Linda Hill; Carol Sipan; Lawrence Friedman Journal: Contemp Clin Trials Commun Date: 2018-08-16