Literature DB >> 12941500

Comparison of three different purification methods for the routine preparation of [11C] Metomidate.

Markus Mitterhauser1, Wolfgang Wadsak, Oliver Langer, Joern Schmaljohann, Georg Zettinig, Robert Dudczak, Helmut Viernstein, Kurt Kletter.   

Abstract

PET with (R)-[O-methyl-11C] metomidate ([11C] MTO) is an attractive method for the characterisation of adrenal masses discriminating lesions of adrenal cortical origin from noncortical lesions. [11C] MTO was prepared by the reaction of [11C] methyliodide with the corresponding free acid. Three purification methods have been compared. The method of choice uses preparative HPLC with a ready-to-use weak acidic solvent.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12941500     DOI： 10.1016/s0969-8043(03)00168-4

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  3 in total

1.  [18F]FETO for adrenocortical PET imaging: a pilot study in healthy volunteers.

Authors:  Wolfgang Wadsak; Markus Mitterhauser; Gundula Rendl; Matthias Schuetz; Leonhard Key Mien; Dagmar E Ettlinger; Robert Dudczak; Kurt Kletter; Georgios Karanikas
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-03-28       Impact factor: 9.236

2.  Positron emission tomography imaging of adrenal masses: (18)F-fluorodeoxyglucose and the 11beta-hydroxylase tracer (11)C-metomidate.

Authors:  Georg Zettinig; Markus Mitterhauser; Wolfgang Wadsak; Alexander Becherer; Christian Pirich; Heinrich Vierhapper; Bruno Niederle; Robert Dudczak; Kurt Kletter
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-06-10       Impact factor: 9.236

Review 3.  Targeted Molecular Imaging in Adrenal Disease-An Emerging Role for Metomidate PET-CT.

Authors:  Iosif A Mendichovszky; Andrew S Powlson; Roido Manavaki; Franklin I Aigbirhio; Heok Cheow; John R Buscombe; Mark Gurnell; Fiona J Gilbert
Journal:  Diagnostics (Basel)       Date:  2016-11-18
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.