| Literature DB >> 12941471 |
Paul Preece1, David J Virley, Moheb Costandi, Robert Coombes, Stephen J Moss, Anne W Mudge, Elena Jazin, Nigel J Cairns.
Abstract
Beta-secretase (BACE) and glycogen synthase kinase (GSK 3) are two enzymes thought to play a role in Alzheimer's disease. We extracted mRNA from 90 Alzheimer and 81 control brains. Levels of mRNA were quantified for BACE and GSK 3 with TaqMan real-time RT-PCR. We found no change in the Alzheimer's disease brains relative to controls for either the BACE or the GSK 3alpha mRNA levels.Entities:
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Year: 2003 PMID： 12941471 DOI： 10.1016/s0169-328x(03)00233-x
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN： 0169-328X