| Literature DB >> 12941414 |
David C Nickle1, Daniel Shriner, John E Mittler, Lisa M Frenkel, James I Mullins.
Abstract
Current therapies for treating HIV-1 infection are capable of suppressing virus load in blood to undetectable levels, and result in marked clinical improvement. Despite this suppression, HIV-1 infection persists and virus load quickly rebounds when therapy is interrupted. The origin of the rebounding virus is unknown, but is thought to result from continuing viral replication in anatomic or cellular compartments, and the release of virus from latent infection in reservoirs.Entities:
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Year: 2003 PMID: 12941414 DOI: 10.1016/s1369-5274(03)00096-1
Source DB: PubMed Journal: Curr Opin Microbiol ISSN: 1369-5274 Impact factor: 7.934