Literature DB >> 12941396

NKT cells and HIV infection.

Derya Unutmaz1.   

Abstract

Natural killer T (NKT) cells are a subset of lymphocytes that express a semi-invariant T cell receptor (TCR) that recognizes glycolipids presented by the non-polymorphic MHC class I-like molecule CD1d. NKT cells regulate a wide variety of immune functions against autoantigens and pathogens. Recently, it was shown that NKT cells are targeted by HIV-1 and selectively lost in HIV-infected individuals. This review will focus on the mechanisms, consequences and therapeutic implications of these findings.

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Year:  2003        PMID： 12941396     DOI： 10.1016/s1286-4579(03)00185-0

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  11 in total

1.  Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients.

Authors:  Karina I Carvalho; Fernanda R Bruno; Jennifer E Snyder-Cappione; Solange M Maeda; Jane Tomimori; Marilia B Xavier; Patrick A Haslett; Douglas F Nixon; Esper G Kallas
Journal:  Immunology       Date:  2012-05       Impact factor: 7.397

2.  CD1d mediates T-cell-dependent resistance to secondary infection with encephalomyocarditis virus (EMCV) in vitro and immune response to EMCV infection in vivo.

Authors:  Petr O Ilyinskii; Ruojie Wang; Steven P Balk; Mark A Exley
Journal:  J Virol       Date:  2006-07       Impact factor: 5.103

Review 3.  HIV infection: focus on the innate immune cells.

Authors:  Milena S Espíndola; Luana S Soares; Leonardo J Galvão-Lima; Fabiana A Zambuzi; Maira C Cacemiro; Verônica S Brauer; Fabiani G Frantz
Journal:  Immunol Res       Date:  2016-12       Impact factor: 2.829

4.  Preferential depletion of gut CD4-expressing iNKT cells contributes to systemic immune activation in HIV-1 infection.

Authors:  F J Ibarrondo; S B Wilson; L E Hultin; R Shih; M A Hausner; P M Hultin; P A Anton; B D Jamieson; O O Yang
Journal:  Mucosal Immunol       Date:  2012-11-14       Impact factor: 7.313

5.  Lower numbers of circulating Natural Killer T (NK T) cells in individuals with human T lymphotropic virus type 1 (HTLV-1) associated neurological disease.

Authors:  L C Ndhlovu; J E Snyder-Cappione; K I Carvalho; F E Leal; C P Loo; F R Bruno; A R Jha; D Devita; A M Hasenkrug; H M R Barbosa; A C Segurado; D F Nixon; E L Murphy; E G Kallas
Journal:  Clin Exp Immunol       Date:  2009-09-02       Impact factor: 4.330

Review 6.  A double-edged sword: the role of NKT cells in malaria and HIV infection and immunity.

Authors:  Sandhya Vasan; Moriya Tsuji
Journal:  Semin Immunol       Date:  2009-12-04       Impact factor: 11.130

7.  Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection.

Authors:  Namita Rout; James G Else; Simon Yue; Michelle Connole; Mark A Exley; Amitinder Kaur
Journal:  PLoS One       Date:  2010-03-24       Impact factor: 3.240

8.  Direct CD1d-mediated stimulation of APC IL-12 production and protective immune response to virus infection in vivo.

Authors:  Simon C Yue; Michael Nowak; Angela Shaulov-Kask; RuoJie Wang; Dominic Yue; Steven P Balk; Mark A Exley
Journal:  J Immunol       Date:  2009-11-30       Impact factor: 5.422

9.  Loss of effector and anti-inflammatory natural killer T lymphocyte function in pathogenic simian immunodeficiency virus infection.

Authors:  Namita Rout; Justin Greene; Simon Yue; David O'Connor; R Paul Johnson; James G Else; Mark A Exley; Amitinder Kaur
Journal:  PLoS Pathog       Date:  2012-09-20       Impact factor: 6.823

Review 10.  Invariant NKT cells: regulation and function during viral infection.

Authors:  Jennifer A Juno; Yoav Keynan; Keith R Fowke
Journal:  PLoS Pathog       Date:  2012-08-16       Impact factor: 6.823
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