| Literature DB >> 12941386 |
Risa Nakata1, Takayuki Miyazawa, Yeon-Sil Shin, Rie Watanabe, Takeshi Mikami, Yoshiharu Matsuura.
Abstract
We reevaluated the host ranges of feline leukemia virus (FeLV) subgroups A, B and C using pseudotype assays based on recombinant NB-tropic murine leukemia virus, which is not usually blocked after viral entry in mammalian cells. Pseudotype viruses of FeLV-B and -C infected a variety of cell lines from many mammalian species. Unexpectedly, FeLV-A pseudotype viruses of two independent isolates from the UK and US also infected a variety of non-feline cell lines including cells from humans, rabbits, pigs and minks. Moreover, both isolates of FeLV-A productively infected human embryonic kidney 293 and mink Mv-1-Lu cells. We conclude that FeLV-A is not strictly ecotropic.Entities:
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Year: 2003 PMID: 12941386 DOI: 10.1016/s1286-4579(03)00180-1
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700