Literature DB >> 12941268

Cell proliferation without cyclin E-CDK2.

Juan Méndez1.   

Abstract

In this issue of Cell, Geng et al. report that mice can undergo embryonic development without cyclins E1 and E2. Fibroblasts derived from the double knockout embryos proliferate normally in culture. However, E type cyclins seem essential for endoreplication and exit from quiescence.

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Year:  2003        PMID: 12941268     DOI: 10.1016/s0092-8674(03)00649-4

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  5 in total

1.  Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies.

Authors:  Glen J Weiss; Manuel Hidalgo; Mitesh J Borad; Daniel Laheru; Raoul Tibes; Ramesh K Ramanathan; Lisa Blaydorn; Gayle Jameson; Antonio Jimeno; Jeffrey D Isaacs; Angela Scaburri; Maria Adele Pacciarini; Francesco Fiorentini; Marina Ciomei; Daniel D Von Hoff
Journal:  Invest New Drugs       Date:  2011-12-09       Impact factor: 3.850

Review 2.  Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors.

Authors:  Nawal Bendris; Bénédicte Lemmers; Jean Marie Blanchard
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

3.  Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells.

Authors:  André Wirries; Sandra Breyer; Karl Quint; Rainer Schobert; Matthias Ocker
Journal:  Exp Ther Med       Date:  2010-03-01       Impact factor: 2.447

4.  Oncological Properties of Intravenous Leiomyomatosis: Involvement of Mesenchymal Tumor Stem-Like Cells.

Authors:  Saya Tamura; Takuma Hayashi; Hideki Tokunaga; Nobuo Yaegashi; Kaoru Abiko; Ikuo Konishi
Journal:  Curr Issues Mol Biol       Date:  2021-09-19       Impact factor: 2.976

5.  The effect of curcumin on the differentiation, apoptosis and cell cycle of neural stem cells is mediated through inhibiting autophagy by the modulation of Atg7 and p62.

Authors:  Jun-Ling Wang; Jian-Jun Wang; Zhen-Nao Cai; Chao-Jin Xu
Journal:  Int J Mol Med       Date:  2018-08-29       Impact factor: 4.101

  5 in total

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