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Literature DB >> 12941029

The evolving role of platelets in inflammation.

A S Weyrich¹, S Lindemann, G A Zimmerman.

Abstract

Platelets are small in size and simple in structure. Nevertheless, these anucleate cytoplasts utilize complex molecular systems to regulate a variety of biological functions. Here we review evolutionary paths, traditional roles, and previously unrecognized biological capacities of platelets that interface thrombosis with inflammation and potentially identify new roles in inflammatory diseases.

Entities: Disease

Mesh：

Substances：
Integrins

Year: 2003 PMID： 12941029 DOI： 10.1046/j.1538-7836.2003.00304.x

Source DB: PubMed Journal: J Thromb Haemost ISSN： 1538-7836 Impact factor: 5.824

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Cited

59 in total

1. Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.

Authors: Stephan W Lindemann; Christian C Yost; Melvin M Denis; Thomas M McIntyre; Andrew S Weyrich; Guy A Zimmerman
Journal: Proc Natl Acad Sci U S A Date: 2004-04-26 Impact factor: 11.205

Review 2. Platelets as central mediators of systemic inflammatory responses.

Authors: Tammy L Smith; Andrew S Weyrich
Journal: Thromb Res Date: 2010-11-11 Impact factor: 3.944

3. Mean platelet volume seems to be a valuable marker in patients with systemic sclerosis.

Authors: Serdar Soydinc; Ibrahim Halil Turkbeyler; Yavuz Pehlivan; Gulcimen Soylu; Mehmet Fatih Goktepe; Muhammed Bilici; Orhan Zengin; Bunyamin Kisacik; Ahmet Mesut Onat
Journal: Inflammation Date: 2014-02 Impact factor: 4.092

4. mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.

Authors: Andrew S Weyrich; Melvin M Denis; Hansjorg Schwertz; Neal D Tolley; Jason Foulks; Eliott Spencer; Larry W Kraiss; Kurt H Albertine; Thomas M McIntyre; Guy A Zimmerman
Journal: Blood Date: 2006-11-16 Impact factor: 22.113

5. Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling.

Authors: Dan A Dixon; Neal D Tolley; Kristi Bemis-Standoli; Mark L Martinez; Andrew S Weyrich; Jason D Morrow; Stephen M Prescott; Guy A Zimmerman
Journal: J Clin Invest Date: 2006-09-21 Impact factor: 14.808

6. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.

Authors: Melvin M Denis; Neal D Tolley; Michaeline Bunting; Hansjörg Schwertz; Huimiao Jiang; Stephan Lindemann; Christian C Yost; Frederick J Rubner; Kurt H Albertine; Kathryn J Swoboda; Carolyn M Fratto; Emilysa Tolley; Larry W Kraiss; Thomas M McIntyre; Guy A Zimmerman; Andrew S Weyrich
Journal: Cell Date: 2005-08-12 Impact factor: 41.582

The evolving role of platelets in inflammation.

1. Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.

Review 2. Platelets as central mediators of systemic inflammatory responses.

3. Mean platelet volume seems to be a valuable marker in patients with systemic sclerosis.

4. mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.

5. Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling.

6. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.

Review 7. The role of platelet CD154 in the modulation in adaptive immunity.

Review 8. Amicus or Adversary Revisited: Platelets in Acute Lung Injury and Acute Respiratory Distress Syndrome.

9. Preoperative serum pattern analysis to predict the outcome of tonsillectomy in adults with chronic tonsillitis.

Review 10. The role of platelets in tumour growth.