Literature DB >> 1293928

[Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma renin activity and angiotensin II level].

F Liu1, Y Wei, X Z Yang, F G Li, J Hu, R F Cheng.   

Abstract

Safflower yellow (SY) is a mixture of chalconoid compounds extracted from Carthamus tinctorius L. Ig SY 1-2 g.kg-1.d-1 lowered the blood pressure of spontaneously hypertensive rats (SHR), for about 1.86-3.86 kPa. Five weeks after administration of SY, the plasma renin activity and angiotensin II level diminished in the SHR experimental groups. These suggest that the decrease of blood pressure is mediated by the renin-angiotensin system.

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Year:  1992        PMID： 1293928

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN： 0513-4870


  5 in total

1.  Neuroprotective effects of safflor yellow B on brain ischemic injury.

Authors:  Chaoyun Wang; Dalei Zhang; Guisheng Li; Juntian Liu; Jingwei Tian; Fenghua Fu; Ke Liu
Journal:  Exp Brain Res       Date:  2006-09-28       Impact factor: 1.972

Review 2.  Medical uses of Carthamus tinctorius L. (Safflower): a comprehensive review from Traditional Medicine to Modern Medicine.

Authors:  Elahe Delshad; Mahdi Yousefi; Payam Sasannezhad; Hasan Rakhshandeh; Zahra Ayati
Journal:  Electron Physician       Date:  2018-04-25

3.  Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway.

Authors:  Donglai Zhou; Tingting Ding; Bin Ni; Yunyan Jing; Shanxin Liu
Journal:  Int J Mol Med       Date:  2019-06-05       Impact factor: 4.101

4.  Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in L-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT₁R Expression.

Authors:  Putcharawipa Maneesai; Patoomporn Prasarttong; Sarawoot Bunbupha; Upa Kukongviriyapan; Veerapol Kukongviriyapan; Panot Tangsucharit; Parichat Prachaney; Poungrat Pakdeechote
Journal:  Nutrients       Date:  2016-02-29       Impact factor: 5.717

5.  Hydroxysafflor yellow A (HSYA) from flowers of Carthamus tinctorius L. and its vasodilatation effects on pulmonary artery.

Authors:  Yuhua Bai; Ping Lu; Chenghua Han; Chunyue Yu; Minggang Chen; Fa He; Dan Yi; Lijun Wu
Journal:  Molecules       Date:  2012-12-13       Impact factor: 4.411
  5 in total

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