Literature DB >> 12939118

Immediate hypersensitivity phenomena in bullous pemphigoid: critical concepts.

Monika Bowszyc-Dmochowska1, Marian Dmochowski.   

Abstract

The immediate hypersensitivity phenomena in bullous pemphigoid (BP) will be discussed in this review. There is prominent involvement of eosinophils in the pathogenesis of human BP. Activation of these eosinophils in BP may lead not only to tissue damage, but also to regulation of the immune response. Stimulation of Th2 cells is responsible for the production of IgG4 and IgE autoantibodies to the hemidesmosomal proteins, 180-kDa BP antigen and 230-kDa BP antigen.

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Year:  2002        PMID： 12939118

Source DB:  PubMed          Journal:  J Med        ISSN： 0025-7850


  6 in total

Review 1.  Non-infectious environmental antigens as a trigger for the initiation of an autoimmune skin disease.

Authors:  Ye Qian; Donna A Culton; Joseph S Jeong; Nicole Trupiano; Jesus G Valenzuela; Luis A Diaz
Journal:  Autoimmun Rev       Date:  2016-07-08       Impact factor: 9.754

Review 2.  Targeted Therapies for Autoimmune Bullous Diseases: Current Status.

Authors:  Kyle T Amber; Roberto Maglie; Farzan Solimani; Rüdiger Eming; Michael Hertl
Journal:  Drugs       Date:  2018-10       Impact factor: 9.546

3.  Eosinophil infiltration in three patients with generalized atrophic benign epidermolysis bullosa from a Japanese family: molecular genetic and immunohistochemical studies.

Authors:  Masayo Nomura; Yoh-Ichiro Hamasaki; Ichiro Katayama; Kuniko Abe; Norio Niikawa; Koh-Ichiro Yoshiura
Journal:  J Hum Genet       Date:  2005-09-20       Impact factor: 3.172

4.  Regulation and dysregulation of immunoglobulin E: a molecular and clinical perspective.

Authors:  Mariah B Pate; John Kelly Smith; David S Chi; Guha Krishnaswamy
Journal:  Clin Mol Allergy       Date:  2010-02-23

5.  Conceptualization and validation of an innovative direct immunofluorescence technique utilizing fluorescein conjugate against IgG + IgG4 for routinely diagnosing autoimmune bullous dermatoses.

Authors:  Magdalena Danuta Jałowska; Justyna Gornowicz-Porowska; Agnieszka Seraszek-Jaros; Monika Bowszyc-Dmochowska; Elżbieta Kaczmarek; Marian Dmochowski
Journal:  Cent Eur J Immunol       Date:  2021-06-15       Impact factor: 2.085

Review 6.  The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease.

Authors:  Kyle T Amber; Manuel Valdebran; Khalaf Kridin; Sergei A Grando
Journal:  Front Med (Lausanne)       Date:  2018-07-10
  6 in total

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