Literature DB >> 12939037

Cytotoxic naphthoquinones from roots of Lippia microphylla.

Hélcio S Santos1, Sônia M O Costa, Otília D L Pessoa, Manoel O Moraes, Claudia Pessoa, Sergio Fortier, Edilberto R Silveira, Telma L G Lemos.   

Abstract

A new prenylated naphthoquinone dimer named microphyllaquinone (1), a mixture of 6-methoxy- and 7-methoxy-naphtho[2,3-b]-furan-4,9-quinones (2a/2b) and tecomaquinone I (3), were isolated from roots of Lippia microphylla. The structures were elucidated by spectroscopic methods, including detailed 1D and 2D (COSY, NOESY, HMQC, HMBC) NMR data. Unpublished 13C NMR data of 2a and 2b are reported. The in vitro cytotoxic activity of the isolated compounds was tested against five types of tumor cells.

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Year:  2003        PMID: 12939037     DOI: 10.1515/znc-2003-7-812

Source DB:  PubMed          Journal:  Z Naturforsch C J Biosci        ISSN: 0341-0382


  1 in total

Review 1.  Biomedical properties and potentiality of Lippia microphylla Cham. and its essential oils.

Authors:  Evelyne Rolim Braun Simões; Evelyne Alves Santos; Maria Carolina de Abreu; Jurandy do Nascimento Silva; Nárcia Mariana Fonseca Nunes; Marcília Pinheiro da Costa; Otília Deusdênia Loiola Pessoa; Cláudia Pessoa; Paulo Michel Pinheiro Ferreira
Journal:  J Intercult Ethnopharmacol       Date:  2015-06-26
  1 in total

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