Literature DB >> 12937974

Selective deficiency of naïve CD4+ T-lymphocytes in a child with congenital lymphoedema.

Elena Chiappini1, Luisa Galli, Maria Grazia Giudizi, Chiara Azzari, Augusto Antonio Niccoli, Sergio Romagnani, Maurizio de Martino.   

Abstract

We describe the first known case of congenital lymphoedema associated with selective deficit of naïve CD4+ T-lymphocytes. A high proportion of naïve CD4+ T-lymphocytes was found in the ascitic fluid, supporting the hypothesis of extra-vascular sequestration of these cells into lymphoedematous tissue.

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Year:  2003        PMID： 12937974     DOI： 10.1007/s00431-003-1295-7

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  8 in total

Review 1.  Primary immunodeficiency diseases. Report of an IUIS Scientific Committee. International Union of Immunological Societies.

Authors: 
Journal:  Clin Exp Immunol       Date:  1999-10       Impact factor: 4.330

2.  Highly active antiretroviral therapy restores in vitro mitogen and antigen-specific T-lymphocyte responses in HIV-1 perinatally infected children despite virological failure.

Authors:  M Peruzzi; C Azzari; L Galli; A Vierucci; M De Martino
Journal:  Clin Exp Immunol       Date:  2002-05       Impact factor: 4.330

3.  Viral load and CD69 molecule expression on freshly isolated and cultured mitogen-stimulated lymphocytes of children with perinatal HIV-1 infection.

Authors:  M De Martino; M E Rossi; C Azzari; M G Gelli; F Chiarelli; L Galli; A Vierucci
Journal:  Clin Exp Immunol       Date:  1999-09       Impact factor: 4.330

4.  A potential role for interleukin-7 in T-cell homeostasis.

Authors:  T J Fry; E Connick; J Falloon; M M Lederman; D J Liewehr; J Spritzler; S M Steinberg; L V Wood; R Yarchoan; J Zuckerman; A Landay; C L Mackall
Journal:  Blood       Date:  2001-05-15       Impact factor: 22.113

5.  Kinetics of B, CD4 T, and CD8 T cells infused into humans: estimates of intravascular:extravascular ratios and total body counts.

Authors:  Jan Storek; Bojan B Lalovic; Kate Rupert; Monja A Dawson; Danny D Shen; David G Maloney
Journal:  Clin Immunol       Date:  2002-03       Impact factor: 3.969

Review 6.  Research perspectives in inherited lymphatic disease.

Authors:  Robert E Ferrell
Journal:  Ann N Y Acad Sci       Date:  2002-12       Impact factor: 5.691

7.  Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia.

Authors:  J Laurence; D Mitra; M Steiner; D H Lynch; F P Siegal; L Staiano-Coico
Journal:  J Clin Invest       Date:  1996-02-01       Impact factor: 14.808

8.  Expanded CD4+CD45RO+ phenotype and defective proliferative response in T lymphocytes from patients with Crohn's disease.

Authors:  L I Roman; L Manzano; A De La Hera; L Abreu; I Rossi; M Alvarez-Mon
Journal:  Gastroenterology       Date:  1996-04       Impact factor: 22.682
  8 in total

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