Amidine-based molecularly imprinted polymers-new sensitive elements for chiral chemosensors.

Using the optical measurement technique reflectometric interference spectroscopy (RIfS), the interaction of molecularly imprinted polymers (imprinted with either (R, R)- or (S, S)-2,3-di- O-benzoyltartraric acid) with the corresponding templates and template antipodes were investigated. With these sensors chiral separation with a separation factor of 1.2 could be achieved whereas a reference polymer resulted in no separation. RIfS signals were of opposite sign for imprinted polymer layers containing phenylboronic acid binding site monomers.