Literature DB >> 12935955

Morphological and cytochemical characteristics of leukaemic promyelocytes.

V Liso1, J Bennett.   

Abstract

Evaluation of cell morphology is usually sufficient to diagnose acute promyelocytic leukaemia (APL). In this chapter we discuss the features of classical hypergranular APL, the APL variant, hyperbasophilic promyelocytic leukaemia, APL with basophil-like granules, acute eosinophilic leukaemia with PML/RARalpha positivity and the morphology of APL cells lacking t(15;17). In addition to morphological examination, cytochemical investigations (peroxidase chloroacetate-esterase, etc.) may help further in defining the cytology of leukaemic cells in APL.

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Mesh：

Year:  2003        PMID： 12935955     DOI： 10.1016/s1521-6926(03)00061-6

Source DB:  PubMed          Journal:  Best Pract Res Clin Haematol        ISSN： 1521-6926            Impact factor:   3.020


  5 in total

1.  Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group.

Authors:  Martin S Tallman; Haesook T Kim; Pau Montesinos; Frederick R Appelbaum; Javier de la Serna; John M Bennett; Guillermo Deben; Clara D Bloomfield; Jose Gonzalez; James H Feusner; Marcos Gonzalez; Robert Gallagher; Jose D Gonzalez-San Miguel; Richard A Larson; Gustavo Milone; Elisabeth Paietta; Chelo Rayon; Jacob M Rowe; Concha Rivas; Charles A Schiffer; Edo Vellenga; Lois Shepherd; James L Slack; Peter H Wiernik; Cheryl L Willman; Miguel A Sanz
Journal:  Blood       Date:  2010-09-21       Impact factor: 22.113

2.  The biological characteristics of adult CD34+ acute promyelocytic leukemia.

Authors:  Ebtesam Ibrahim Ahmad; Hosneia Kh Akl; Mona E Hashem; Tarek Ali M Elgohary
Journal:  Med Oncol       Date:  2011-03-12       Impact factor: 3.064

Review 3.  Current first- and second-line treatment options in acute promyelocytic leukemia.

Authors:  Fulvio Massaro; Matteo Molica; Massimo Breccia
Journal:  Int J Hematol Oncol       Date:  2017-02-02

Review 4.  Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis.

Authors:  Luca Guarnera; Tiziana Ottone; Emiliano Fabiani; Mariadomenica Divona; Arianna Savi; Serena Travaglini; Giulia Falconi; Paola Panetta; Maria Cristina Rapanotti; Maria Teresa Voso
Journal:  Front Oncol       Date:  2022-04-12       Impact factor: 5.738

5.  Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Authors:  E H A Dekking; V H J van der Velden; R Varro; H Wai; S Böttcher; M Kneba; E Sonneveld; A Koning; N Boeckx; N Van Poecke; P Lucio; A Mendonça; L Sedek; T Szczepański; T Kalina; V Kanderová; P Hoogeveen; J Flores-Montero; M C Chillón; A Orfao; J Almeida; P Evans; M Cullen; A L Noordijk; P M Vermeulen; M T de Man; E P Dixon; W M Comans-Bitter; J J M van Dongen
Journal:  Leukemia       Date:  2012-05-08       Impact factor: 11.528
  5 in total

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