BACKGROUND: Anesthetized morbidly obese patients often exhibit impaired pulmonary gas exchanges, mostly because of a reduction in functional residual capacity. At present, several approaches are suggested to ventilate these patients. METHODS: The efficiency of positive end-expiratory pressure (PEEP) and reverse Trendelenburg position (RTP) were compared in order to improve oxygenation in 20 morbidly obese patients undergoing bariatric surgery. RESULTS: Both PEEP and RTP determined a significant decrease in alveolar-arterial oxygen difference and an increase in total respiratory compliance (Ctot). RTP resulted in lower airway pressures than PEEP with similar improvements in Ctot and oxygenation. Concerning hemodynamic parameters, cardiac output (CO) significantly decreased with both PEEP and RTP. CONCLUSIONS: RTP and PEEP can be considered adequate ventilatory settings for morbidly obese patients, without any significant difference with regard to gas exchange improvement. However, the decrease in CO may partially counteract the beneficial effects on oxygenation of these ventilatory settings.
BACKGROUND: Anesthetized morbidly obesepatients often exhibit impaired pulmonary gas exchanges, mostly because of a reduction in functional residual capacity. At present, several approaches are suggested to ventilate these patients. METHODS: The efficiency of positive end-expiratory pressure (PEEP) and reverse Trendelenburg position (RTP) were compared in order to improve oxygenation in 20 morbidly obesepatients undergoing bariatric surgery. RESULTS: Both PEEP and RTP determined a significant decrease in alveolar-arterial oxygen difference and an increase in total respiratory compliance (Ctot). RTP resulted in lower airway pressures than PEEP with similar improvements in Ctot and oxygenation. Concerning hemodynamic parameters, cardiac output (CO) significantly decreased with both PEEP and RTP. CONCLUSIONS: RTP and PEEP can be considered adequate ventilatory settings for morbidly obesepatients, without any significant difference with regard to gas exchange improvement. However, the decrease in CO may partially counteract the beneficial effects on oxygenation of these ventilatory settings.
Authors: Roop Kaw; Loutfi Aboussouan; Dennis Auckley; Charles Bae; David Gugliotti; Paul Grant; Wael Jaber; Philip Schauer; Daniel Sessler Journal: Obes Surg Date: 2007-11-16 Impact factor: 4.129
Authors: Francesco Forfori; Salvatore Mario Romano; Tania Balderi; Marco Anselmino; Francesco Giunta Journal: Obes Surg Date: 2008-10-23 Impact factor: 4.129
Authors: Luis I Cortínez; Brian J Anderson; Nick H G Holford; Valentina Puga; Natalia de la Fuente; Hernán Auad; Sandra Solari; Fidel A Allende; Mauricio Ibacache Journal: Eur J Clin Pharmacol Date: 2015-09-26 Impact factor: 2.953