Literature DB >> 12933887

Intracellular survival of Streptococcus pyogenes in polymorphonuclear cells results in increased bacterial virulence.

Eva Medina1, Manfred Rohde, Gursharan S Chhatwal.   

Abstract

It has recently been shown that survival within phagocytic cells constitutes an additional strategy used by Streptococcus pyogenes to evade the host defenses. Here we provide evidence that S. pyogenes can escape from the phagosome into the cytoplasm of phagocytic cells. Furthermore, intracellular bacteria seem to undergo phenotypic switching that results in much more virulent microorganisms.

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Year:  2003        PMID： 12933887      PMCID： PMC187312          DOI： 10.1128/IAI.71.9.5376-5380.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

1.  Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection.

Authors:  N C Engleberg; A Heath; A Miller; C Rivera; V J DiRita
Journal:  J Infect Dis       Date:  2001-03-01       Impact factor: 5.226

Review 2.  Streptococcal M protein: molecular design and biological behavior.

Authors:  V A Fischetti
Journal:  Clin Microbiol Rev       Date:  1989-07       Impact factor: 26.132

3.  Genetic control of susceptibility to group A streptococcal infection in mice.

Authors:  E Medina; O Goldmann; M Rohde; A Lengeling; G S Chhatwal; G S Chhatwals
Journal:  J Infect Dis       Date:  2001-08-29       Impact factor: 5.226

4.  Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis.

Authors:  B Lei; F R DeLeo; N P Hoe; M R Graham; S M Mackie; R L Cole; M Liu; H R Hill; D E Low; M J Federle; J R Scott; J M Musser
Journal:  Nat Med       Date:  2001-12       Impact factor: 53.440

5.  Characterization of a mouse-passaged, highly encapsulated variant of group A streptococcus in in vitro and in vivo studies.

Authors:  M Ravins; J Jaffe; E Hanski; I Shetzigovski; S Natanson-Yaron; A E Moses
Journal:  J Infect Dis       Date:  2000-10-18       Impact factor: 5.226

Review 6.  Group A streptococci in the 1990s.

Authors:  A Efstratiou
Journal:  J Antimicrob Chemother       Date:  2000-02       Impact factor: 5.790

7.  Immune mechanisms underlying host susceptibility to infection with group A streptococci.

Authors:  Oliver Goldmann; Gursharan Singh Chhatwal; Eva Medina
Journal:  J Infect Dis       Date:  2003-02-24       Impact factor: 5.226

8.  Survival of Streptococcus pyogenes within host phagocytic cells: a pathogenic mechanism for persistence and systemic invasion.

Authors:  Eva Medina; Oliver Goldmann; Antonia W Toppel; Gursharan S Chhatwal
Journal:  J Infect Dis       Date:  2003-02-07       Impact factor: 5.226

9.  Role of streptolysin O in a mouse model of invasive group A streptococcal disease.

Authors:  B Limbago; V Penumalli; B Weinrick; J R Scott
Journal:  Infect Immun       Date:  2000-11       Impact factor: 3.441

10.  Reduced virulence of group A streptococcal Tn916 mutants that do not produce streptolysin S.

Authors:  S D Betschel; S M Borgia; N L Barg; D E Low; J C De Azavedo
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441
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  21 in total

1.  SpyA, a C3-like ADP-ribosyltransferase, contributes to virulence in a mouse subcutaneous model of Streptococcus pyogenes infection.

Authors:  Jessica S Hoff; Mark DeWald; Steve L Moseley; Carleen M Collins; Jovanka M Voyich
Journal:  Infect Immun       Date:  2011-03-21       Impact factor: 3.441

Review 2.  Toward a genome-wide systems biology analysis of host-pathogen interactions in group A Streptococcus.

Authors:  James M Musser; Frank R DeLeo
Journal:  Am J Pathol       Date:  2005-12       Impact factor: 4.307

3.  Serine/threonine phosphatase (SP-STP), secreted from Streptococcus pyogenes, is a pro-apoptotic protein.

Authors:  Shivani Agarwal; Shivangi Agarwal; Hong Jin; Preeti Pancholi; Vijay Pancholi
Journal:  J Biol Chem       Date:  2012-01-19       Impact factor: 5.157

Review 4.  Group A Streptococcus encounters with host macrophages.

Authors:  J Andrés Valderrama; Victor Nizet
Journal:  Future Microbiol       Date:  2017-12-11       Impact factor: 3.165

5.  The Streptococcus iniae transcriptional regulator CpsY is required for protection from neutrophil-mediated killing and proper growth in vitro.

Authors:  Jonathan P Allen; Melody N Neely
Journal:  Infect Immun       Date:  2011-09-12       Impact factor: 3.441

6.  D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion.

Authors:  Sascha A Kristian; Vivekanand Datta; Christopher Weidenmaier; Rita Kansal; Iris Fedtke; Andreas Peschel; Richard L Gallo; Victor Nizet
Journal:  J Bacteriol       Date:  2005-10       Impact factor: 3.490

7.  Morphotypic conversion in Listeria monocytogenes biofilm formation: biological significance of rough colony isolates.

Authors:  Ian R Monk; Gregory M Cook; Brian C Monk; Philip J Bremer
Journal:  Appl Environ Microbiol       Date:  2004-11       Impact factor: 4.792

8.  SalY of the Streptococcus pyogenes lantibiotic locus is required for full virulence and intracellular survival in macrophages.

Authors:  Hilary A Phelps; Melody N Neely
Journal:  Infect Immun       Date:  2007-06-18       Impact factor: 3.441

9.  Intranasal bacteria induce Th1 but not Treg or Th2.

Authors:  M Costalonga; P P Cleary; L A Fischer; Z Zhao
Journal:  Mucosal Immunol       Date:  2008-10-08       Impact factor: 7.313

10.  IL-1α-induced microvascular endothelial cells promote neutrophil killing by increasing MMP-9 concentration and lysozyme activity.

Authors:  Xiaoye Liu; Hong Dong; Mingming Wang; Ying Gao; Tao Zhang; Ge Hu; Huiqing Duan; Xiang Mu
Journal:  Immunol Res       Date:  2016-02       Impact factor: 2.829
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