| Literature DB >> 12932908 |
Vera L de M Guarda1, Monique Perrissin, François Thomasson, Eulalia A Ximenes, Suely L Galdino, Ivan R Pitta, Cuong Luu-Duc, Jacques Barbe.
Abstract
Synthesis, physical and analytical properties of 6-alkylacylamino-4-octyl-2H-1,4-benzo-thiazin-3-ones derivatives are described. These new compounds were prepared by acylation and/or alkylation of the amino group under phase transfer catalysis conditions. Acid hydrolysis of the alkylacylamino-2H-1,4-benzo-thiazin-3-ones afforded N-alkylamino-benzothiazin-3-ones. Some of these compounds were evaluated in vitro for possible bacteriostatic activity.Entities:
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Year: 2003 PMID： 12932908 DOI： 10.1016/s0223-5234(03)00127-2
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514