| Literature DB >> 12932144 |
Naoya Oku1, Shigeki Matsunaga, Rob W M van Soest, Nobuhiro Fusetani.
Abstract
Renieramycin J (1), a new tetrahydroisoquinoline alkaloid, has been isolated from a marine sponge Neopetrosia sp. as a potent cytotoxin that induced morphological changes in 3Y1 cells. Such changes are characteristic of RNA and/or protein synthesis inhibitors. The structure of 1 including the absolute stereochemistry was determined by spectroscopic and chemical methods.Entities:
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Year: 2003 PMID： 12932144 DOI： 10.1021/np030092g
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050