Literature DB >> 12932128

Eudesmane derivatives and other sesquiterpenes from Laggera alata.

Qun Xiong Zheng1, Zhao Jun Xu, Xian Feng Sun, Françoise Guéritte, Michele Cesario, Han Dong Sun, Christopher H K Cheng, Xiao-Jiang Hao, Yu Zhao.   

Abstract

Three new eudesmane sesquiterpenes, 5 beta-hydroxyilicic acid (1), 5 alpha-hydroxyl-4-epi-ilicic acid methyl ester (2), and 3 alpha-hydroxyilicic acid (3), together with 12 known sesquiterpenes were isolated from the aerial part of Laggera alata. Their structures were elucidated primarily by NMR and mass spectroscopic methods. The structures of 1 and 2 were confirmed by X-ray crystallography.

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Year:  2003        PMID: 12932128     DOI: 10.1021/np0205856

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Biochemical conservation and evolution of germacrene A oxidase in asteraceae.

Authors:  Don Trinh Nguyen; Jens Christian Göpfert; Nobuhiro Ikezawa; Gillian Macnevin; Meena Kathiresan; Jürgen Conrad; Otmar Spring; Dae-Kyun Ro
Journal:  J Biol Chem       Date:  2010-03-29       Impact factor: 5.157

2.  Anti-hepatitis B virus effect and possible mechanism of action of 3,4-o-dicaffeoylquinic Acid in vitro and in vivo.

Authors:  Yi-Hang Wu; Bing-Jie Hao; Hong-Cui Cao; Wei Xu; Yong-Jun Li; Lan-Juan Li
Journal:  Evid Based Complement Alternat Med       Date:  2012-06-03       Impact factor: 2.629

3.  Protective Properties of Laggera alata Extract and its Principle Components Against d-Galactosamine-Injured Hepatocytes.

Authors:  Yi-Hang Wu; Bing-Jie Hao; E Shen; Qing-Li Meng; Ming-Hui Hu; Yu Zhao
Journal:  Sci Pharm       Date:  2012-02-08

4.  Isochlorogenic Acid A Attenuates the Progression of Liver Fibrosis Through Regulating HMGB1/TLR4/NF-κB Signaling Pathway.

Authors:  Xin Liu; Kai Huang; Ru Jiao Zhang; Dan Mei; Bo Zhang
Journal:  Front Pharmacol       Date:  2020-05-01       Impact factor: 5.810

5.  Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus.

Authors:  Hang Qi; Yuntao Shi; Han Wu; Canyang Niu; Xiaoying Sun; KeWei Wang
Journal:  Acta Pharm Sin B       Date:  2021-08-05       Impact factor: 11.413

  5 in total

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