| Literature DB >> 12932127 |
Biao Yao1, Michèle R Prinsep, Brian K Nicholson, Dennis P Gordon.
Abstract
Two new alkaloids, pterocellins A and B, have been isolated from the New Zealand marine bryozoan Pterocella vesiculosa. Structural elucidation was achieved through NMR and mass spectral analysis in conjunction with a single-crystal X-ray diffraction study of pterocellin A. The pterocellins possess a novel heterocyclic skeleton and exhibit potent antitumor activity and antimicrobial activity in vitro but only modest activity in the in vivo hollow fiber assay at the National Cancer Institute.Entities:
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Year: 2003 PMID： 12932127 DOI： 10.1021/np030104y
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050