Literature DB >> 12932032

A facile aminocyclization for the synthesis of pyrrolidine and piperidine derivatives.

Zhihui Shao1, Jingbo Chen, Yongqiang Tu, Liang Li, Hongbin Zhang.   

Abstract

Bromination of an isolated double bond followed by aminocyclization furnishes a highly stereoselective protocol for the intramolecular formation of pyrrolidine and piperidine ring containing subunits that are presented in numerous biologically active natural products.

Entities:  

Year:  2003        PMID： 12932032

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  A 5 + 1 Protic Acid Assisted Aza-Pummerer Approach for Synthesis of 4-Chloropiperidines from Homoallylic Amines.

Authors:  Rene Ebule; Sagar Mudshinge; Michael H Nantz; Mark S Mashuta; Gerald B Hammond; Bo Xu
Journal:  J Org Chem       Date:  2019-02-27       Impact factor: 4.354

2.  Influence of solvent mixture on nucleophilicity parameters: the case of pyrrolidine in methanol-acetonitrile.

Authors:  Salma Souissi; Wahiba Gabsi; Abderraouf Echaieb; Julien Roger; Jean-Cyrille Hierso; Paul Fleurat-Lessard; Taoufik Boubaker
Journal:  RSC Adv       Date:  2020-08-03       Impact factor: 4.036
  2 in total

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