Literature DB >> 12931957

Acoustic startle and prepulse inhibition in 40 inbred strains of mice.

James F Willott1, Lisa Tanner, Jennifer O'Steen, Kenneth R Johnson, Molly A Bogue, Leona Gagnon.   

Abstract

A high-throughput phenotype screening protocol was used to measure the acoustic startle response (ASR) and prepulse inhibition (PPI) in mice. ASRs were evoked by noise bursts; prepulses for PPI were 70 dB sound pressure level tones of 4, 12, and 20 kHz. Forty inbred strains of mice were tested (in most cases using 10 males and 10 females of each strain). The data on both the ASR and PPI had high internal and test-retest reliability and showed large differences among inbred strains, indicative of strong genetic influences. Previously obtained measures of hearing sensitivity in the same inbred strains were not significantly correlated with ASR or PPI measures.

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Mesh：

Year:  2003        PMID： 12931957     DOI： 10.1037/0735-7044.117.4.716

Source DB:  PubMed          Journal:  Behav Neurosci        ISSN： 0735-7044            Impact factor:   1.912


  46 in total

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7.  Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice.

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8.  Differences in startle reflex and prepulse inhibition in European-Americans and African-Americans.

Authors:  Wendy Hasenkamp; Seth D Norrholm; Amanda Green; Barbara Lewison; William Boshoven; Megan Keyes; Erica Duncan
Journal:  Psychophysiology       Date:  2008-07-24       Impact factor: 4.016

9.  Genetic background differences and nonassociative effects in mouse trace fear conditioning.

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Review 10.  Human hereditary hearing impairment: mouse models can help to solve the puzzle.

Authors:  Karen Vrijens; Lut Van Laer; Guy Van Camp
Journal:  Hum Genet       Date:  2008-09-11       Impact factor: 4.132
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