Literature DB >> 12931861

New monordens produced by amidepsine-producing fungus Humicola sp. FO-2942.

Masayoshi Arai1, Kazunobu Yamamoto, Ichiji Namatame, Hiroshi Tomoda, Satoshi Omura.   

Abstract

Based on UV spectrum-guided purification, new monordens C, D and E, known monordens A (radicicol) and B and 5-O-methylsclerone were isolated from the fermentation broth of amidepsine-producing Humicola sp. FO-2942 by solvent extraction, silica-gel column chromatography, ODS column chromatography and HPLC. All monordens cause the cell cycle arrest at G1 and G2/M phases in Jurkat cells. But among them, monordens A and E show antifungal activity only against Aspergillus niger.

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Year:  2003        PMID： 12931861     DOI： 10.7164/antibiotics.56.526

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  5 in total

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5.  Napthrene Compounds from Mycelial Fermentation Products of Marasmius berteroi.

Authors:  Ning Ning Yang; Qing Yun Ma; Fan Dong Kong; Qing Yi Xie; Hao Fu Dai; Li Man Zhou; Zhi Fang Yu; You Xing Zhao
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  5 in total

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