Literature DB >> 1293014

Effects of plant extract Centella asiatica (Linn.) on cold restraint stress ulcer in rats.

T K Chatterjee1, A Chakraborty, M Pathak, G C Sengupta.   

Abstract

Extract of C. asiatica (Linn.) inhibited significantly gastric ulceration induced by cold and restraint stress (CRS) in Charles-Foster rats, Antiulcer activity of plant extract was compared with famotidine (H2-antagonist) and sodium valproate (anti-epileptic). Plant extract, formotidine and sodium valproate showed a dose dependent reduction of gastric ulceration. Plant extract increased brain GABA level which was also dose dependent. Pretreatment with bicuculline methiodide (specific GABAA-antagonist) at the dose level of 0.5 mg/kg im, reversed the antiulcerogenic activity of both plant extract and sodium valproate. Bicuculline as such did not induce gastric ulceration in normal rat.

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Year:  1992        PMID： 1293014

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  8 in total

Review 1.  Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review.

Authors:  Farshad Abedi Torbati; Mahin Ramezani; Reza Dehghan; Mohammad Sadegh Amiri; Ali Tafazoli Moghadam; Neda Shakour; Sepideh Elyasi; Amirhossein Sahebkar; Seyed Ahmad Emami
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Asiaticoside, a trisaccaride triterpene induces biochemical and molecular variations in brain of mice with parkinsonism.

Authors:  Uvarajan Sampath; Vanisree Arambakkam Janardhanam
Journal:  Transl Neurodegener       Date:  2013-11-21       Impact factor: 8.014

3.  Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all.

Authors:  Kashmira J Gohil; Jagruti A Patel; Anuradha K Gajjar
Journal:  Indian J Pharm Sci       Date:  2010-09       Impact factor: 0.975

4.  Use of medicinal plants for headache, and their potential implication in medication-overuse headache: Evidence from a population-based study in Nepal.

Authors:  Elise Øien Sørnes; Ajay Risal; Kedar Manandhar; Hallie Thomas; Timothy J Steiner; Mattias Linde
Journal:  Cephalalgia       Date:  2021-01-12       Impact factor: 6.292

5.  A Comparative Study of the Hepatoprotective Effect of Centella asiatica Extract (CA-HE50) on Lipopolysaccharide/d-galactosamine-Induced Acute Liver Injury in C57BL/6 Mice.

Authors:  Woojae Hong; Jeon Hwang-Bo; Hyelin Jeon; Minsung Ko; Joongyeon Choi; Yong-Joon Jeong; Jae-Hyun Park; Inhye Kim; Tae-Woo Kim; Hyunggun Kim; Se-Chan Kang
Journal:  Nutrients       Date:  2021-11-15       Impact factor: 5.717

6.  Critical evaluation of ayurvedic plants for stimulating intrinsic antioxidant response.

Authors:  Sunil Dutt Shukla; Maheep Bhatnagar; Sukant Khurana
Journal:  Front Neurosci       Date:  2012-07-26       Impact factor: 4.677

7.  Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer.

Authors:  Lugkana Mato; Jintanaporn Wattanathorn; Supaporn Muchimapura; Terdthai Tongun; Nawanant Piyawatkul; Kwanchanok Yimtae; Panida Thanawirattananit; Bungorn Sripanidkulchai
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-07       Impact factor: 2.629

Review 8.  Traditional medicines in Africa: an appraisal of ten potent african medicinal plants.

Authors:  M Fawzi Mahomoodally
Journal:  Evid Based Complement Alternat Med       Date:  2013-12-03       Impact factor: 2.629
  8 in total

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