Literature DB >> 12929845

Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan.

Kyung W Kim1, R L Thomas, Chan Lee, Hyun J Park.   

Abstract

The antimicrobial activity of native chitosan was compared to that of lipase-degraded chitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated. The antimicrobial activity of native chitosan was more extensive than that of lipase-degraded chitosan; however, lipase-degraded chitosan was still highly effective and more water-soluble. O-CM chitosan derived from degraded chitosan was more effective than O-CM chitosan derived from native chitosan. O-CM substitution enhanced lipase-degraded chitosan's antimicrobial activity without reducing its solubility.

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Year:  2003        PMID: 12929845     DOI: 10.4315/0362-028x-66.8.1495

Source DB:  PubMed          Journal:  J Food Prot        ISSN: 0362-028X            Impact factor:   2.077


  11 in total

1.  Injectable thermosensitive hydrogel based on chitosan and quaternized chitosan and the biomedical properties.

Authors:  Qiu Xia Ji; Xi Guang Chen; Qing Sheng Zhao; Cheng Sheng Liu; Xiao Jie Cheng; Ling Chong Wang
Journal:  J Mater Sci Mater Med       Date:  2009-03-26       Impact factor: 3.896

2.  Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis.

Authors:  Karen E Beenken; James K Smith; Robert A Skinner; Sandra G Mclaren; William Bellamy; M Johannes Gruenwald; Horace J Spencer; Jessica A Jennings; Warren O Haggard; Mark S Smeltzer
Journal:  J Biomater Appl       Date:  2014-05-21       Impact factor: 2.646

3.  Development of three-dimensional biomimetic scaffold to study epithelial-mesenchymal interactions.

Authors:  Sriram Ravindran; Yiqiang Song; Anne George
Journal:  Tissue Eng Part A       Date:  2010-01       Impact factor: 3.845

4.  Biomimetic extracellular matrix-incorporated scaffold induces osteogenic gene expression in human marrow stromal cells.

Authors:  Sriram Ravindran; Qi Gao; Mrignayani Kotecha; Richard L Magin; Sachin Karol; Ana Bedran-Russo; Anne George
Journal:  Tissue Eng Part A       Date:  2011-10-24       Impact factor: 3.845

5.  Periodontal tissue regeneration using enzymatically solidified chitosan hydrogels with or without cell loading.

Authors:  Xiang-Zhen Yan; Jeroen J J P van den Beucken; Xinjie Cai; Na Yu; John A Jansen; Fang Yang
Journal:  Tissue Eng Part A       Date:  2014-12-11       Impact factor: 3.845

6.  PROTEIN TEMPLATES IN HARD TISSUE ENGINEERING.

Authors:  Anne George; Sriram Ravindran
Journal:  Nano Today       Date:  2010-08-01       Impact factor: 20.722

Review 7.  Surface coating of orthopedic implant to enhance the osseointegration and reduction of bacterial colonization: a review.

Authors:  Smriti Bohara; Jackrit Suthakorn
Journal:  Biomater Res       Date:  2022-06-20

Review 8.  Biomimetic extracellular matrix mediated somatic stem cell differentiation: applications in dental pulp tissue regeneration.

Authors:  Sriram Ravindran; Anne George
Journal:  Front Physiol       Date:  2015-04-21       Impact factor: 4.566

9.  Chitosomes-In-Chitosan Hydrogel for Acute Skin Injuries: Prevention and Infection Control.

Authors:  Lisa Myrseth Hemmingsen; Kjersti Julin; Luqman Ahsan; Purusotam Basnet; Mona Johannessen; Nataša Škalko-Basnet
Journal:  Mar Drugs       Date:  2021-05-12       Impact factor: 5.118

10.  Imaging-Guided Delivery of a Hydrophilic Drug to Eukaryotic Cells Based on Its Hydrophobic Ion Pairing with Poly(hexamethylene guanidine) in a Maleated Chitosan Carrier.

Authors:  Sofia A Zakharenkova; Marina I Lebedeva; Alexandra N Lebedeva; Irina A Doroshenko; Ksenya Yu Vlasova; Anastasiya A Bartoshevich; Vladimir M Senyavin; Sergey S Abramchuk; George G Krivtsov; Alexander A Ezhov; Tatyana A Podrugina; Natalia L Klyachko; Mikhail K Beklemishev
Journal:  Molecules       Date:  2021-12-07       Impact factor: 4.411

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