Literature DB >> 12929624

The aryl hydrocarbon receptor and its xenobiotic ligands: a fundamental trigger for cardiovascular diseases.

J F Savouret1, A Berdeaux, R F Casper.   

Abstract

This review reconsiders a major cause of cardiovascular diseases, tobacco smoking, as the activation of the Aryl hydrocarbon Receptor (AhR), also known as the dioxin receptor, by aryl hydrocarbons from the tar fraction of tobacco in various organs of the cardiovascular domain. This concept sheds new light on well-known albeit controversial epidemiological concepts such as the Mediterranean diet and the French paradox. We also review the discovery that resveratrol, a natural AhR antagonist, may be of interest in the prevention and treatment of cardiovascular diseases.

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Year:  2003        PMID： 12929624     DOI： 10.1016/s0939-4753(03)80026-1

Source DB:  PubMed          Journal:  Nutr Metab Cardiovasc Dis        ISSN： 0939-4753            Impact factor:   4.222


  22 in total

1.  Is alcohol anti-inflammatory in the context of coronary heart disease?

Authors:  M de Lorgeril; P Salen
Journal:  Heart       Date:  2004-04       Impact factor: 5.994

2.  Aryl Hydrocarbon Receptor Repressor Methylation: A Link Between Smoking and Atherosclerosis.

Authors:  John W Cole; Huichun Xu
Journal:  Circ Cardiovasc Genet       Date:  2015-10

3.  ITE inhibits growth of human pulmonary artery endothelial cells.

Authors:  Ling-Pin Pang; Yan Li; Qing-Yun Zou; Chi Zhou; Wei Lei; Jing Zheng; Shi-An Huang
Journal:  Exp Lung Res       Date:  2017-10       Impact factor: 2.459

4.  Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR).

Authors:  Seung-Hyeon Seok; Zhi-Xiong Ma; John B Feltenberger; Hongbo Chen; Hui Chen; Cameron Scarlett; Ziqing Lin; Kenneth A Satyshur; Marissa Cortopassi; Colin R Jefcoate; Ying Ge; Weiping Tang; Christopher A Bradfield; Yongna Xing
Journal:  J Biol Chem       Date:  2017-12-26       Impact factor: 5.157

5.  Signaling network map of the aryl hydrocarbon receptor.

Authors:  Soujanya D Yelamanchi; Hitendra Singh Solanki; Aneesha Radhakrishnan; Lavanya Balakrishnan; Jayshree Advani; Remya Raja; Nandini A Sahasrabuddhe; Premendu Prakash Mathur; Pinaki Dutta; T S Keshava Prasad; Márta Korbonits; Aditi Chatterjee; Harsha Gowda; Kanchan Kumar Mukherjee
Journal:  J Cell Commun Signal       Date:  2016-07-27       Impact factor: 5.782

6.  Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphenyl toxicity in endothelial cells.

Authors:  Lei Wang; Gudrun Reiterer; Michal Toborek; Bernhard Hennig
Journal:  Chem Biol Interact       Date:  2007-11-19       Impact factor: 5.192

7.  Coplanar polychlorinated biphenyl-induced CYP1A1 is regulated through caveolae signaling in vascular endothelial cells.

Authors:  Eun Jin Lim; Zuzana Májková; Shifen Xu; Leonidas Bachas; Xabier Arzuaga; Eric Smart; Michael T Tseng; Michal Toborek; Bernhard Hennig
Journal:  Chem Biol Interact       Date:  2008-08-22       Impact factor: 5.192

Review 8.  Biochemical effects of SIRT1 activators.

Authors:  Joseph A Baur
Journal:  Biochim Biophys Acta       Date:  2009-11-06

9.  DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis.

Authors:  Lindsay M Reynolds; Ma Wan; Jingzhong Ding; Jackson R Taylor; Kurt Lohman; Dan Su; Brian D Bennett; Devin K Porter; Ryan Gimple; Gary S Pittman; Xuting Wang; Timothy D Howard; David Siscovick; Bruce M Psaty; Steven Shea; Gregory L Burke; David R Jacobs; Stephen S Rich; James E Hixson; James H Stein; Hendrik Stunnenberg; R Graham Barr; Joel D Kaufman; Wendy S Post; Ina Hoeschele; David M Herrington; Douglas A Bell; Yongmei Liu
Journal:  Circ Cardiovasc Genet       Date:  2015-08-25

10.  Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells.

Authors:  Pankaj Dabir; Tina E Marinic; Irene Krukovets; Olga I Stenina
Journal:  Circ Res       Date:  2008-05-30       Impact factor: 17.367
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