Literature DB >> 12929380

Development of beta-keto 1,3-dithianes as versatile intermediates for organic synthesis.

Matthew J Gaunt1, Helen F Sneddon, Peter R Hewitt, Paolo Orsini, David F Hook, Steven V Ley.   

Abstract

beta-Keto 1,3-dithianes can be generated by the double conjugate addition of dithiols to propargylic ketones, esters and aldehydes in excellent yields. As masked 1,3-dicarbonyl systems these substrates can be converted to a range of functionalised oxygen-containing heterocycles that can be used in natural product synthesis.

Entities:  

Year:  2003        PMID： 12929380     DOI： 10.1039/b208982c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.

Authors:  Sumit Mukherjee; Dimitra Kontokosta; Aditi Patil; Sivakumar Rallapalli; Daesung Lee
Journal:  J Org Chem       Date:  2009-12-04       Impact factor: 4.354

2.  Application of tandem ring-closing enyne metathesis: formal total synthesis of (-)-cochleamycin A.

Authors:  Sumit Mukherjee; Daesung Lee
Journal:  Org Lett       Date:  2009-07-02       Impact factor: 6.005

3.  Diversity-oriented synthesis based on the DPPP-catalyzed mixed double-Michael reactions of electron-deficient acetylenes and β-amino alcohols.

Authors:  Yi Chiao Fan; Ohyun Kwon
Journal:  Molecules       Date:  2011-05-05       Impact factor: 4.411

4.  Callipeltosides A, B and C: Total Syntheses and Structural Confirmation.

Authors:  James R Frost; Colin M Pearson; Thomas N Snaddon; Richard A Booth; Richard M Turner; Johan Gold; David M Shaw; Matthew J Gaunt; Steven V Ley
Journal:  Chemistry       Date:  2015-07-31       Impact factor: 5.236
  4 in total

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