Literature DB >> 12929238

Inertial shear forces and the use of centrifuges in gravity research. What is the proper control?

Jack J van Loon1, Erik H Folgering, Carlijn V Bouten, J Paul Veldhuijzen, Theo H Smit.   

Abstract

Centrifuges are used for 1 x g controls in space flight microgravity experiments and in ground based research. Using centrifugation as a tool to generate an Earth like acceleration introduces unwanted inertial shear forces to the sample. Depending on the centrifuge and the geometry of the experiment hardware used these shear forces contribute significantly to the total force acting on the cells or tissues. The inertial shear force artifact should be dealt with for future experiment hardware development for Shuttle and the International Space Station (ISS) as well as for the interpretation of previous space-flight and on-ground research data.

Mesh:

Year:  2003        PMID: 12929238     DOI: 10.1115/1.1574521

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  17 in total

Review 1.  Space, the final frontier: A critical review of recent experiments performed in microgravity.

Authors:  Joshua P Vandenbrink; John Z Kiss
Journal:  Plant Sci       Date:  2015-11-07       Impact factor: 4.729

2.  Measuring Intracellular Viscosity in Conditions of Hypergravity.

Authors:  Emma M Woodcock; Paul Girvan; Julia Eckert; Ismael Lopez-Duarte; Markéta Kubánková; Jack J W A van Loon; Nicholas J Brooks; Marina K Kuimova
Journal:  Biophys J       Date:  2019-04-08       Impact factor: 4.033

3.  Effects of hypergravity on the angiogenic potential of endothelial cells.

Authors:  Raquel Costa-Almeida; Daniel T O Carvalho; Miguel J S Ferreira; Guilherme Aresta; Manuela E Gomes; Jack J W A van Loon; Kim Van der Heiden; Pedro L Granja
Journal:  J R Soc Interface       Date:  2016-11       Impact factor: 4.118

4.  High-selectivity cytology via lab-on-a-disc western blotting of individual cells.

Authors:  John J Kim; Elly Sinkala; Amy E Herr
Journal:  Lab Chip       Date:  2017-02-28       Impact factor: 6.799

Review 5.  Space microbiology.

Authors:  Gerda Horneck; David M Klaus; Rocco L Mancinelli
Journal:  Microbiol Mol Biol Rev       Date:  2010-03       Impact factor: 11.056

6.  Molecular impact of launch related dynamic vibrations and static hypergravity in planarians.

Authors:  Nídia de Sousa; Marcello Caporicci; Jeroen Vandersteen; Jose Ignacio Rojo-Laguna; Emili Saló; Teresa Adell; Gennaro Auletta; Jack J W A van Loon
Journal:  NPJ Microgravity       Date:  2020-09-08       Impact factor: 4.415

7.  Hypergravity affects cell traction forces of fibroblasts.

Authors:  Julia Eckert; Jack J W A van Loon; Lukas M Eng; Thomas Schmidt
Journal:  Biophys J       Date:  2021-03-02       Impact factor: 4.033

8.  Suboptimal evolutionary novel environments promote singular altered gravity responses of transcriptome during Drosophila metamorphosis.

Authors:  Raul Herranz; Oliver J Larkin; Richard J A Hill; Irene Lopez-Vidriero; Jack J W A van Loon; F Javier Medina
Journal:  BMC Evol Biol       Date:  2013-06-27       Impact factor: 3.260

9.  Transient Intervals of Hyper-Gravity Enhance Endothelial Barrier Integrity: Impact of Mechanical and Gravitational Forces Measured Electrically.

Authors:  Robert Szulcek; Jan van Bezu; Johannes Boonstra; Jack J W A van Loon; Geerten P van Nieuw Amerongen
Journal:  PLoS One       Date:  2015-12-04       Impact factor: 3.240

10.  Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1.

Authors:  Elisabeth Warnke; Jessica Pietsch; Markus Wehland; Johann Bauer; Manfred Infanger; Mark Görög; Ruth Hemmersbach; Markus Braun; Xiao Ma; Jayashree Sahana; Daniela Grimm
Journal:  Cell Commun Signal       Date:  2014-05-10       Impact factor: 5.712

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