Literature DB >> 12927384

The use of solid self-emulsifying systems in the delivery of diclofenac.

A A Attama1, I T Nzekwe, P O Nnamani, M U Adikwu, C O Onugu.   

Abstract

Goat fat and Tween 65 admixtures were used to formulate self-emulsifying tablets containing diclofenac. The tablets were formulated by pour moulding using a plastic mould. The tablets were evaluated using the following parameters: weight uniformity, absolute drug content, and liquefaction time. The dissolution profile of diclofenac from the self-emulsifying tablets was determined in simulated gastric fluid (SGF) without pepsin. Results obtained indicated that diclofenac could be comfortably administered in the form of self-emulsifying tablets using goat fat and Tween 65 admixtures.

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Year:  2003        PMID： 12927384     DOI： 10.1016/s0378-5173(03)00315-6

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  9 in total

1.  Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery system (SEDDS) of ketoprofen.

Authors:  Pradeep Patil; Prasad Joshi; Anant Paradkar
Journal:  AAPS PharmSciTech       Date:  2004-07-22       Impact factor: 3.246

2.  Porous polystyrene beads as carriers for self-emulsifying system containing loratadine.

Authors:  Pradeep Patil; Anant Paradkar
Journal:  AAPS PharmSciTech       Date:  2006-03-24       Impact factor: 3.246

3.  Extended release felodipine self-nanoemulsifying system.

Authors:  Pradeep R Patil; Shailesh V Biradar; Anant R Paradkar
Journal:  AAPS PharmSciTech       Date:  2009-05-05       Impact factor: 3.246

4.  Calcium Alginate-Neusilin US2 Nanocomposite Microbeads for Oral Sustained Drug Delivery of Poor Water Soluble Drug Aceclofenac Sodium.

Authors:  Manjanna Kolammanahalli Mallappa; Rajesh Kesarla; Shivakumar Banakar
Journal:  J Drug Deliv       Date:  2015-02-23

5.  Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1.

Authors:  Yongtao Tong; Yuli Wang; Meiyan Yang; Jiahui Yang; Lu Chen; Xiaoyang Chu; Chunhong Gao; Qian Jin; Wei Gong; Chunsheng Gao
Journal:  Pharmaceutics       Date:  2018-07-18       Impact factor: 6.321

Review 6.  Lipid-based colloidal carriers for peptide and protein delivery--liposomes versus lipid nanoparticles.

Authors:  Susana Martins; Bruno Sarmento; Domingos C Ferreira; Eliana B Souto
Journal:  Int J Nanomedicine       Date:  2007

7.  Development and Evaluation of Novel Self-Nanoemulsifying Drug Delivery Systems Based on a Homolipid from Capra hircus and Its Admixtures with Melon Oil for the Delivery of Indomethacin.

Authors:  Nicholas C Obitte; Kenneth C Ofokansi; Franklin C Kenechukwu
Journal:  J Pharm (Cairo)       Date:  2014-03-20

8.  SHSST cyclodextrin complex prevents the fibrosis effect on CCl₄-induced cirrhotic cardiomyopathy in rats through TGF-β pathway inhibition effects.

Authors:  Cheng-Hsun Yang; Wei-Jen Ting; Cecilia Hsuan Day; Da-Tong Ju; Yu-Lan Yeh; Li-Chin Chung; Fu-Jenn Tsai; Chang-Hai Tsai; Yuhsin Tsai; Chih-Yang Huang
Journal:  Int J Mol Sci       Date:  2014-05-08       Impact factor: 5.923

9.  Sustained-release liquisolid compact tablets containing artemether-lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance.

Authors:  Petra Obioma Nnamani; Agatha Adaora Ugwu; Emmanuel Chinedu Ibezim; Franklin Chimaobi Kenechukwu; Paul Achile Akpa; John-Dike Nwabueze Ogbonna; Nicholas Chinedu Obitte; Amelia Ngozi Odo; Maike Windbergs; Claus-Michael Lehr; Anthony Amaechi Attama
Journal:  Int J Nanomedicine       Date:  2016-11-28
  9 in total

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