Literature DB >> 12926358

Preparation and in vitro evaluation of GdDOTA-(BOM)4; a novel angiographic MRI contrast agent.

Ragnar Hovland1, Arne J Aasen, Jo Klaveness.   

Abstract

A novel Gd(III) complex, GdDOTA-(BOM)4, has been prepared by a simple three-step procedure. The complex showed high T1-relaxivity values in serum albumin solutions, blood and plasma, resulting from high affinity for serum albumin. The T1-relaxivity in plasma, 67.4 s-1 mM-1 (20 MHz, 37 degrees C), makes it a promising candidate for angiographic applications of MRI.

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Year:  2003        PMID： 12926358     DOI： 10.1039/b301944f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

Review 1.  Chemical exchange saturation transfer contrast agents for magnetic resonance imaging.

Authors:  A Dean Sherry; Mark Woods
Journal:  Annu Rev Biomed Eng       Date:  2008       Impact factor: 9.590

2.  Albumin-binding PARACEST agents.

Authors:  M Meser Ali; Mark Woods; Eul Hyun Suh; Zoltan Kovacs; Gyula Tircsó; Piyu Zhao; Vikram D Kodibagkar; A Dean Sherry
Journal:  J Biol Inorg Chem       Date:  2007-05-30       Impact factor: 3.358

3.  Self-Assembling Metallocomplexes of the Amphiphilic 1,4-Diazabicyclo[2.2.2]octane Derivative as a Platform for the Development of Nonplatinum Anticancer Drugs.

Authors:  Lucia Ya Zakharova; Alexandra D Voloshina; Marina R Ibatullina; Elena P Zhiltsova; Svetlana S Lukashenko; Darya A Kuznetsova; Marianna P Kutyreva; Anastasiia S Sapunova; Anna A Kufelkina; Natalia V Kulik; Olga Kataeva; Kamil A Ivshin; Aidar T Gubaidullin; Vadim V Salnikov; Irek R Nizameev; Marsil K Kadirov; Oleg G Sinyashin
Journal:  ACS Omega       Date:  2022-01-14
  3 in total

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