Literature DB >> 12923840

From model complexes to metalloprotein inhibition: a synergistic approach to structure-based drug discovery.

David T Puerta1, Julie R Schames, Richard H Henchman, J Andrew McCammon, Seth M Cohen.   

Abstract

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Year:  2003        PMID： 12923840     DOI： 10.1002/anie.200351433

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  11 in total

1.  Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

Authors:  Jennifer A Jacobsen; Jessica L Fullagar; Melissa T Miller; Seth M Cohen
Journal:  J Med Chem       Date:  2010-12-28       Impact factor: 7.446

2.  A Bioinorganic Approach to Fragment-Based Drug Discovery Targeting Metalloenzymes.

Authors:  Seth M Cohen
Journal:  Acc Chem Res       Date:  2017-07-17       Impact factor: 22.384

3.  Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1.

Authors:  Allie Y Chen; Pei W Thomas; Alesha C Stewart; Alexander Bergstrom; Zishuo Cheng; Callie Miller; Christopher R Bethel; Steven H Marshall; Cy V Credille; Christopher L Riley; Richard C Page; Robert A Bonomo; Michael W Crowder; David L Tierney; Walter Fast; Seth M Cohen
Journal:  J Med Chem       Date:  2017-08-30       Impact factor: 7.446

4.  Effect of donor atom identity on metal-binding pharmacophore coordination.

Authors:  Benjamin L Dick; Ashay Patel; J Andrew McCammon; Seth M Cohen
Journal:  J Biol Inorg Chem       Date:  2017-04-07       Impact factor: 3.358

5.  Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.

Authors:  Douglas R Hurst; Martin A Schwartz; Yonghao Jin; Mohammad A Ghaffari; Pallavi Kozarekar; Jian Cao; Qing-Xiang Amy Sang
Journal:  Biochem J       Date:  2005-12-15       Impact factor: 3.857

6.  From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis.

Authors:  Sarah L Williams; César Augusto F de Oliveira; H Vazquez; J Andrew McCammon
Journal:  Chem Biol Drug Des       Date:  2011-02       Impact factor: 2.817

7.  Pyrone-based inhibitors of metalloproteinase types 2 and 3 may work as conformation-selective inhibitors.

Authors:  Jacob D Durrant; César A F de Oliveira; J Andrew McCammon
Journal:  Chem Biol Drug Des       Date:  2011-06-20       Impact factor: 2.817

8.  'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.

Authors:  David P Martin; Patrick G Blachly; Amy R Marts; Tessa M Woodruff; César A F de Oliveira; J Andrew McCammon; David L Tierney; Seth M Cohen
Journal:  J Am Chem Soc       Date:  2014-03-27       Impact factor: 15.419

9.  Exploring the influence of the protein environment on metal-binding pharmacophores.

Authors:  David P Martin; Patrick G Blachly; J Andrew McCammon; Seth M Cohen
Journal:  J Med Chem       Date:  2014-08-19       Impact factor: 7.446

10.  Including receptor flexibility and induced fit effects into the design of MMP-2 inhibitors.

Authors:  Jacob D Durrant; César Augusto F de Oliveira; J Andrew McCammon
Journal:  J Mol Recognit       Date:  2010 Mar-Apr       Impact factor: 2.137
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