| Literature DB >> 12923661 |
H E Lee1, V J Marder, L J Logan, S Friedman, B J Miller.
Abstract
We report a patient with hemoglobin sickle cell-hemoglobin C disease who developed the clinical syndrome of thrombotic thrombocytopenic purpura (TTP) during admission for typical acute pain crisis. The potential for multiorgan involvement secondary to vaso-occlusive crisis complicated the diagnosis and overlapped with the patient's clinical presentation of chronic bone pain and hemolytic anemia. Clinical improvement and normalization of laboratory parameters followed rapidly in response to plasma exchange therapy.Entities:
Mesh：
Year: 2003 PMID： 12923661 DOI： 10.1007/s00277-003-0715-0
Source DB: PubMed Journal: Ann Hematol ISSN： 0939-5555 Impact factor: 3.673