| Literature DB >> 12923631 |
Alexandre de Sá-Freire1, José Luciano Nepomuceno-Silva, Júlio César da Paixão, Sérgio Maurício de Mendonça, Luiz Dione Barbosa de Melo, Ulisses Gazos Lopes.
Abstract
Arfs (ADP-ribosylation factors) are conserved GTP-binding proteins involved in the control of coatomers assembling in budding vesicles in the eukaryotic secretory pathway and during some endocytic events. Here, we describe the gene for an Arf-homologue from the unicellular kinetoplastid parasite Trypanosoma cruzi, named TcArf1. TcArf1 is present in a discrete copy number in the T. cruzi genome and is expressed as a 1-kb transcript in the three main life forms of the parasite. Increased mRNA expression in epimastigotes may correlate with abundant protein biosynthesis and endocytosis in this stage.Entities:
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Year: 2003 PMID： 12923631 DOI： 10.1007/s00436-003-0952-0
Source DB: PubMed Journal: Parasitol Res ISSN： 0932-0113 Impact factor: 2.289