Literature DB >> 12923617

A survey on patients admitted in severe coma: implications for brain death identification and organ donation.

Kamel Senouci1, Patrice Guerrini, Eloi Diene, Alain Atinault, Jacky Claquin, Francis Bonnet, Philippe Tuppin.   

Abstract

OBJECTIVE: To identify factors to improve the identification of brain dead patients in intensive care units (ICUs). DESIGN AND
SETTING: Prospective study conducted in 79 ICUs in 54 hospitals. PATIENTS: All hospitalized patients with a Glasgow Coma Scale (GCS) score less than 8. MEASUREMENTS AND
RESULTS: During the study period hospital staff completed a form for each patient with a GCS less than 8. Hospital information units provided us with statistics from the discharge forms. The characteristics of the hospitals were also recorded. We included a total of 792 patients with a GCS less than 8; 120 of these patients were diagnosed as being clinically brain dead (15.1%). These patients accounted for 11.8% of the comatose patients in ICUs, 11.7% of the deaths occurring in ICUs, and 3.3% of the deaths that occurred in the hospital during the study period. Two multivariate linear regressions were performed to predict the number of clinically brain dead patients in the ICUs. The regression analyses included causes of death or causes of coma, and hospital characteristics. The presence of a coordination team and the number of transplant coordinators were positively associated with the number of brain dead patients in both models. The number of patients carried to the ICU by a mobile emergency unit was also positively associated in the model with causes of coma.
CONCLUSIONS: Increasing the number of hospital coordinators and collaboration with mobile emergency units should lead to the identification of more brain dead patients among comatose patients in ICUs.

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Mesh:

Year:  2003        PMID: 12923617     DOI: 10.1007/s00134-003-1923-8

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  13 in total

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10.  Donor Action: an international initiative to alleviate organ shortage.

Authors:  L Roels; C Wight
Journal:  Prog Transplant       Date:  2001-06       Impact factor: 1.065

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  5 in total

Review 1.  Supply and demand of organs for donation.

Authors:  Gilbert Park
Journal:  Intensive Care Med       Date:  2003-11-29       Impact factor: 17.440

Review 2.  Year in review in intensive care medicine, 2004. II. Brain injury, hemodynamic monitoring and treatment, pulmonary embolism, gastrointestinal tract, and renal failure.

Authors:  Peter Andrews; Elie Azoulay; Massimo Antonelli; Laurent Brochard; Christian Brun-Buisson; Geoffrey Dobb; Jean-Yves Fagon; Herwig Gerlach; Johan Groeneveld; Jordi Mancebo; Philipp Metnitz; Stefano Nava; Jerome Pugin; Michael Pinsky; Peter Radermacher; Christian Richard; Robert Tasker; Benoit Vallet
Journal:  Intensive Care Med       Date:  2005-01-28       Impact factor: 17.440

3.  Organ donations and unused potential donations in traumatic brain injury, subarachnoid haemorrhage and intracerebral haemorrhage.

Authors:  Erwin J O Kompanje; Jan Bakker; François J A Slieker; Jan N M IJzermans; Andrew I R Maas
Journal:  Intensive Care Med       Date:  2006-01-24       Impact factor: 17.440

4.  Determining the impact of timing and of clinical factors during end-of-life decision-making in potential controlled donation after circulatory death donors.

Authors:  Angela M Kotsopoulos; Nichon E Jansen; Piet Vos; Marloes Witjes; Meint Volbeda; Jelle L Epker; Hans P C Sonneveld; Koen S Simons; Ewald M Bronkhorst; Hans G van der Hoeven; Wilson F Abdo
Journal:  Am J Transplant       Date:  2020-08-26       Impact factor: 8.086

5.  Is informed consent required for the diagnosis of brain death regardless of consent for organ donation?

Authors:  Osamu Muramoto
Journal:  J Med Ethics       Date:  2020-06-05       Impact factor: 2.903

  5 in total

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