OBJECTIVE: To compare the clinic significance of three lung function markers after cardiopulmonary bypass operation. METHODS:Twenty-four patients who continuously took selective coronary artery bypass grafting (CABG) with cardiopulmonary bypass in our hospital were separated randomly to AT group and non AT group according the different treatments of the residue blood in extracorporeal circulation (ECC) circuit, 12 patients in each group. The data of hemodynamics and oxygenation after anesthesia induction and 1, 6, 24, 48 h after ECC were recorded. Respiratory index (RI), oxygenation index (OI) and M index (PaO2/PAO2) were counted and compared at the same time. RESULTS: CI, O2ER, DO2I and VO2I were all elevated obviously after ECC, and Qs/Qt were decreased. There were no difference of all these markers between two groups. RI, OI and PaO2/PAO2 did not change during perioperation in AT group, but in non AT group, RI was increased after ECC, company with the decrease of OI and PaO2/PAO2 at the same time. Nevertheless there was no difference between two groups. But the alterations of the marker percentages were more obviously, there were marked differences between the percentages of RI and PaO2/PAO2 24 h after ECC. All three markers had correlation with Qs/Qt and VO2I. CONCLUSION: RI, OI and PaO2/PAO2 all can reflect appropriately the change of lung function after extracorporeal circulation and the monitor of the developmental alterations individually may be more instructive in clinical practice.
RCT Entities:
OBJECTIVE: To compare the clinic significance of three lung function markers after cardiopulmonary bypass operation. METHODS: Twenty-four patients who continuously took selective coronary artery bypass grafting (CABG) with cardiopulmonary bypass in our hospital were separated randomly to AT group and non AT group according the different treatments of the residue blood in extracorporeal circulation (ECC) circuit, 12 patients in each group. The data of hemodynamics and oxygenation after anesthesia induction and 1, 6, 24, 48 h after ECC were recorded. Respiratory index (RI), oxygenation index (OI) and M index (PaO2/PAO2) were counted and compared at the same time. RESULTS: CI, O2ER, DO2I and VO2I were all elevated obviously after ECC, and Qs/Qt were decreased. There were no difference of all these markers between two groups. RI, OI and PaO2/PAO2 did not change during perioperation in AT group, but in non AT group, RI was increased after ECC, company with the decrease of OI and PaO2/PAO2 at the same time. Nevertheless there was no difference between two groups. But the alterations of the marker percentages were more obviously, there were marked differences between the percentages of RI and PaO2/PAO2 24 h after ECC. All three markers had correlation with Qs/Qt and VO2I. CONCLUSION: RI, OI and PaO2/PAO2 all can reflect appropriately the change of lung function after extracorporeal circulation and the monitor of the developmental alterations individually may be more instructive in clinical practice.