| Literature DB >> 12920048 |
Burton E Sobel1, Douglas J Taatjes, David J Schneider.
Abstract
Altered expression of plasminogen activator inhibitor type-1 in vessel walls, reviewed here, might affect coronary atherogenesis. Upregulation might exacerbate vasculopathy by potentiating thrombosis and by inhibiting vascular smooth muscle cell migration, resulting in attenuation of thickness of elaborated fibrous caps implicated in the vulnerability of atheroma to rupture.Entities:
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Year: 2003 PMID: 12920048 DOI: 10.1161/01.ATV.0000091250.53231.4D
Source DB: PubMed Journal: Arterioscler Thromb Vasc Biol ISSN: 1079-5642 Impact factor: 8.311