| Literature DB >> 12918877 |
Abstract
The role of neuropeptide Y (NPY) in feeding behavior and zinc deficiency-induced anorexia has been controversial because hypothalamic NPY levels are elevated in both zinc deficiency and food restriction. A recent report shows that while NPY is released from terminals in the paraventricular nucleus of the hypothalamus of food-restricted animals, this release is significantly impaired in zinc-deficient animals. Zinc deficiency may therefore cause anorexia by inhibiting the release of NPY that is required for receptor activation.Entities:
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Year: 2003 PMID： 12918877 DOI： 10.1301/nr.2003.jul.247-249
Source DB: PubMed Journal: Nutr Rev ISSN： 0029-6643 Impact factor: 7.110