Literature DB >> 12918222

Synthesis and antibacterial activity of 1,3-diarylpyrimido[4,5-d]pyrimidines.

J Cieplik1, J Pluta, O Gubrynowicz.   

Abstract

This paper describes the synthesis of 4,5-diaminoderivatives of pyrimidine and pyrimido [4,5-d] pyrimidines and evaluation of their antibacterial activity on 9 selected bacterial species relatif the changes in the chemical structure to an increase in the bioactive properties.

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Year:  2003        PMID： 12918222

Source DB:  PubMed          Journal:  Boll Chim Farm        ISSN： 0006-6648


  5 in total

1.  5-[(4-Eth-oxy-anilino)meth-yl]-N-(2-fluoro-phen-yl)-6-methyl-2-phenyl-pyrimidin-4-amine.

Authors:  Jerzy Cieplik; Marcin Stolarczyk; Iwona Bryndal; Tadeusz Lis
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-05-16

2.  N-(2-Fluoro-phen-yl)-5-[(4-meth-oxy-phen-yl)amino-meth-yl]-6-methyl-2-phenyl-pyrimidin-4-amine.

Authors:  Jerzy Cieplik; Janusz Pluta; Iwona Bryndal; Tadeusz Lis
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-11-05

3.  A New Pyrimidine Schiff Base with Selective Activities against Enterococcus faecalis and Gastric Adenocarcinoma.

Authors:  Marcin Stolarczyk; Aleksandra Wolska; Aleksandra Mikołajczyk; Iwona Bryndal; Jerzy Cieplik; Tadeusz Lis; Agnieszka Matera-Witkiewicz
Journal:  Molecules       Date:  2021-04-15       Impact factor: 4.411

4.  5-[(4-Fluoro-anilino)meth-yl]-6-methyl-N-(4-methyl-phen-yl)-2-phenyl-pyrimidin-4-amine.

Authors:  Jerzy Cieplik; Marcin Stolarczyk; Iwona Bryndal; Tadeusz Lis
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-09-12

5.  5-[(3,5-Dichloro-anilino)meth-yl]-N-(3,5-dichloro-phen-yl)-6-methyl-2-phenyl-pyrimidin-4-amine.

Authors:  Jerzy Cieplik; Janusz Pluta; Iwona Bryndal; Tadeusz Lis
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-11-24
  5 in total

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