OBJECTIVE: To assess immediate and near-term effects of 2 exercise training programs for persons with idiopathic Parkinson's disease (IPD). DESIGN: Randomized control trial. SETTING: Public health facility and medical center. PARTICIPANTS: Fifteen persons with IPD. INTERVENTION: Combined group (balance and resistance training) and balance group (balance training only) underwent 10 weeks of high-intensity resistance training (knee extensors and flexors, ankle plantarflexion) and/or balance training under altered visual and somatosensory sensory conditions, 3 times a week on nonconsecutive days. Groups were assessed before, immediately after training, and 4 weeks later. MAIN OUTCOME MEASURES: Balance was assessed by computerized dynamic posturography, which determined the subject's response to reduced or altered visual and somatosensory orientation cues (Sensory Orientation Test [SOT]). Muscle strength was assessed by measuring the amount of weight a participant could lift, by using a standardized weight-and-pulley system, during a 4-repetition-maximum test of knee extension, knee flexion, and ankle plantarflexion. RESULTS: Both types of training improved SOT performance. This effect was larger in the combined group. Both groups could balance longer before falling, and this effect persisted for at least 4 weeks. Muscle strength increased marginally in the balance group and substantially in the combined group, and this effect persisted for at least 4 weeks. CONCLUSION:Muscle strength and balance can be improved in persons with IPD by high-intensity resistance training and balance training.
RCT Entities:
OBJECTIVE: To assess immediate and near-term effects of 2 exercise training programs for persons with idiopathic Parkinson's disease (IPD). DESIGN: Randomized control trial. SETTING: Public health facility and medical center. PARTICIPANTS: Fifteen persons with IPD. INTERVENTION: Combined group (balance and resistance training) and balance group (balance training only) underwent 10 weeks of high-intensity resistance training (knee extensors and flexors, ankle plantarflexion) and/or balance training under altered visual and somatosensory sensory conditions, 3 times a week on nonconsecutive days. Groups were assessed before, immediately after training, and 4 weeks later. MAIN OUTCOME MEASURES: Balance was assessed by computerized dynamic posturography, which determined the subject's response to reduced or altered visual and somatosensory orientation cues (Sensory Orientation Test [SOT]). Muscle strength was assessed by measuring the amount of weight a participant could lift, by using a standardized weight-and-pulley system, during a 4-repetition-maximum test of knee extension, knee flexion, and ankle plantarflexion. RESULTS: Both types of training improved SOT performance. This effect was larger in the combined group. Both groups could balance longer before falling, and this effect persisted for at least 4 weeks. Muscle strength increased marginally in the balance group and substantially in the combined group, and this effect persisted for at least 4 weeks. CONCLUSION: Muscle strength and balance can be improved in persons with IPD by high-intensity resistance training and balance training.
Authors: Fuzhong Li; Peter Harmer; Kathleen Fitzgerald; Elizabeth Eckstrom; Ronald Stock; Johnny Galver; Gianni Maddalozzo; Sara S Batya Journal: N Engl J Med Date: 2012-02-09 Impact factor: 91.245
Authors: Arlène D Speelman; Bart P van de Warrenburg; Marlies van Nimwegen; Giselle M Petzinger; Marten Munneke; Bastiaan R Bloem Journal: Nat Rev Neurol Date: 2011-07-12 Impact factor: 42.937
Authors: Claire L Tomlinson; Clare P Herd; Carl E Clarke; Charmaine Meek; Smitaa Patel; Rebecca Stowe; Katherine H O Deane; Laila Shah; Catherine M Sackley; Keith Wheatley; Natalie Ives Journal: Cochrane Database Syst Rev Date: 2014-06-17
Authors: Daniel M Corcos; Julie A Robichaud; Fabian J David; Sue E Leurgans; David E Vaillancourt; Cynthia Poon; Miriam R Rafferty; Wendy M Kohrt; Cynthia L Comella Journal: Mov Disord Date: 2013-03-27 Impact factor: 10.338
Authors: David Sparrow; Tamara R DeAngelis; Kathryn Hendron; Cathi A Thomas; Marie Saint-Hilaire; Terry Ellis Journal: J Neurol Phys Ther Date: 2016-01 Impact factor: 3.649