Literature DB >> 12917453

Phylogenetic analysis of hepatitis C virus isolates indicates a unique pattern of endemic infection in Cameroon.

Jean Ndjomou1, Oliver G Pybus2, Bertfried Matz1.   

Abstract

Hepatitis C virus (HCV) is a blood-borne pathogen that poses a significant threat to public health worldwide. The genetic diversity and distribution of HCV genotypes in non-Western countries, particularly subSaharan Africa, is poorly documented. This study reports a phylogenetic analysis of core and NS5B gene sequences of 37 HCV strains sampled in Cameroon. A high level of genetic diversity of both genotypes 1 and 4 was found, indicating a unique pattern of long-term HCV infection that has not been observed elsewhere. These results lead to the hypothesis that these HCV genotypes originated and diversified in west Central Africa before spreading to other regions.

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Year:  2003        PMID： 12917453     DOI： 10.1099/vir.0.19240-0

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  31 in total

1.  Identification of a naturally occurring recombinant genotype 2/6 hepatitis C virus.

Authors:  Suwanna Noppornpanth; Truong Xuan Lien; Yong Poovorawan; Saskia L Smits; Albert D M E Osterhaus; Bart L Haagmans
Journal:  J Virol       Date:  2006-08       Impact factor: 5.103

2.  Hepatitis C in Cameroon: What is the progress from 2001 to 2016?

Authors:  Borris Rosnay Tietcheu Galani; Richard Njouom; Paul Fewou Moundipa
Journal:  J Transl Int Med       Date:  2016-12-30

3.  Genotype distribution and molecular epidemiology of hepatitis C virus in blood donors from southeast France.

Authors:  Jean-François Cantaloube; Pierre Gallian; Houssam Attoui; Philippe Biagini; Philippe De Micco; Xavier de Lamballerie
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

4.  The full-length genome sequences of nine HCV genotype 4 variants representing a new subtype 4s and eight unclassified lineages.

Authors:  Ling Lu; Yan Xu; Jie Yuan; Chunhua Li; Donald G Murphy
Journal:  Virology       Date:  2015-04-05       Impact factor: 3.616

5.  HCV genotype distribution and possible transmission risks in Lahore, Pakistan.

Authors:  Waqar Ahmad; Bushra Ijaz; Fouzia-Tahir Javed; Shah Jahan; Imran Shahid; Fawad-Mumtaz Khan; Sajida Hassan
Journal:  World J Gastroenterol       Date:  2010-09-14       Impact factor: 5.742

6.  Conservation in China of a novel group of HCV variants dating to six centuries ago.

Authors:  Yuling An; Tao Wu; Min Wang; Ling Lu; Chunhua Li; Yuanpin Zhou; Yongshui Fu; Guihua Chen
Journal:  Virology       Date:  2014-07-18       Impact factor: 3.616

7.  Screening for hepatitis C virus infection in a high prevalence country by an antigen/antibody combination assay versus a rapid test.

Authors:  Claude Tayou Tagny; Dora Mbanya; Edward L Murphy; Jean-Jacques Lefrère; Syria Laperche
Journal:  J Virol Methods       Date:  2014-01-30       Impact factor: 2.014

8.  Complete genomic sequences for hepatitis C virus subtypes 4b, 4c, 4d, 4g, 4k, 4l, 4m, 4n, 4o, 4p, 4q, 4r and 4t.

Authors:  Chunhua Li; Ling Lu; Xianghong Wu; Chuanxi Wang; Phil Bennett; Teng Lu; Donald Murphy
Journal:  J Gen Virol       Date:  2009-04-08       Impact factor: 3.891

9.  A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame.

Authors:  Thomas Kuntzen; Andrew Berical; Jean Ndjomou; Phil Bennett; Arne Schneidewind; Niall Lennon; Bruce W Birren; Carla Kuiken; Matthew R Henn; Peter Simmonds; Todd M Allen
Journal:  J Med Virol       Date:  2008-08       Impact factor: 2.327

10.  Predictors of sustained virological response to a 48-week course of pegylated interferon alfa-2a and ribavirin in patients infected with hepatitis C virus genotype 4.

Authors:  Hamad Al Ashgar; Ahmed Helmy; Mohamed Q Khan; Khalid Al Kahtani; Mohammed Al Quaiz; Mohammed Rezeig; Ingvar Kagevi; Abdullah Alshehri; Abdullah Al Kalbani; Khalid Al Swat; Salim Dahab; Naser Elkum; Mohammed Al Fadda
Journal:  Ann Saudi Med       Date:  2009 Jan-Feb       Impact factor: 1.526
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