| Literature DB >> 12916996 |
David Rodríguez1, Luis Castedo, Domingo Domínguez, Carlos Saá.
Abstract
[reaction: see text] A conceptually new approach to the tetracyclic core of the anthracycline antibiotics is reported. With use of this approach, the 7,8,9,10-tetrahydronaphthacene-5,12-dione skeleton has been synthesized in three steps, from commercially available reagents, in yields of up to 85%.Entities:
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Year: 2003 PMID： 12916996 DOI： 10.1021/ol035168e
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005