Literature DB >> 12916541

Aplastic anaemia: a review.

S Sleijfer1, P J Lugtenburg.   

Abstract

Aplastic anaemia is featured by bone marrow hypocellularity and peripheral pancytopenia and is a potentially fatal disease. In recent years, insight in it pathogenesis has increased. It appears that activated autoreactive T lymphocytes induce apoptosis of haematopoietic stem cells resulting in a hypocellular bone marrow. Nowadays, it can be treated by stem cell transplantation or immunosuppressive therapy. This review focuses on the pathophysiology and treatment of aplastic anaemia.

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Year:  2003        PMID： 12916541

Source DB:  PubMed          Journal:  Neth J Med        ISSN： 0300-2977            Impact factor:   1.422


  3 in total

Review 1.  Meta-analysis of Huangqi injection for the adjunctive therapy of aplastic anemia.

Authors:  Changtai Zhu; Yulu Gao; Ting Jiang; Cao Hao; Zongshuai Gao; Yongning Sun
Journal:  Int J Clin Exp Med       Date:  2015-07-15

2.  Evaluation of Bone Marrow Microvessel Density in Patients with Aplastic Anemia.

Authors:  Venkatesan Somasundaram; Manvir Singh Tevatia; Abhishek Purohit; Ankur Ahuja; Manoranjan Mahapatra; Seema Tyagi; Haraprasad Pati; Renu Saxena
Journal:  Indian J Hematol Blood Transfus       Date:  2016-07-19       Impact factor: 0.900

Review 3.  Special issues related to the diagnosis and management of acquired aplastic anemia in countries with restricted resources, a report on behalf of the Eastern Mediterranean blood and marrow transplantation (EMBMT) group and severe aplastic anemia working party of the European Society for blood and marrow transplantation (SAAWP of EBMT).

Authors:  Raheel Iftikhar; Parvez Ahmad; Regis de Latour; Carlo Dufour; Antonio Risitano; Naeem Chaudhri; Ali Bazarbachi; Josu De La Fuente; Britta Höchsmann; Syed Osman Ahmed; Usama Gergis; Alaa Elhaddad; Constantijn Halkes; Bassim Albeirouti; Sultan Alotaibi; Austin Kulasekararaj; Hazzaa Alzahrani; Tarek Ben Othman; Simone Cesaro; Ali Alahmari; Rawad Rihani; Salem Alshemmari; Amir Ali Hamidieh; Mohamed-Amine Bekadja; Jakob Passweg; Murtadha Al-Khabori; Walid Rasheed; Andrea Bacigalupo; Qamar-Un-Nisa Chaudhry; Per Ljungman; Judith Marsh; Riad El Fakih; Mahmoud Aljurf
Journal:  Bone Marrow Transplant       Date:  2021-05-19       Impact factor: 5.483
  3 in total

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