| Literature DB >> 12914404 |
K P Mellwig1, H K Schmidt, A Brettschneider-Meyer, H Meyer, B R Jaeger, A K Walli, D Seidel, D Horstkotte.
Abstract
In children with familial hypercholesterolemia, coronary heart disease requires both medical theraphy and LDL apheresis. We report a case of verified occlusion of the anterior descending branch of the left coronary artery in a 10-year-old patient. The pathological findings revealed by ergometry established the diagnosis. The goal was to achieve the greatest possible reduction of lipid parameters and fibrinogen by lowering plasma viscosity employing LDL apheresis. It is astonishing that this treatment is also well tolerated by children. The basic vascular approaches suffice and shunt operations are not absolutely necessary. The efficacy of this method became vividly apparent by the changes in the skin lesions. Additional angiographic follow-up and further clinical course wil provide information on the usefulness of this treatment strategy with maximum lipid theraphy and the expected improvement in prognosis.Entities:
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Year: 2003 PMID： 12914404 DOI： 10.1007/s00108-002-0832-1
Source DB: PubMed Journal: Internist (Berl) ISSN： 0020-9554 Impact factor: 0.743