Literature DB >> 12914400

[Autoimmune thyroiditis. Treatment with thyroid gland hormones in subclinical hypothyroidism or already in euthyroid state?].

K H Usadel1, P M Schumm-Draeger.   

Abstract

In patients with subclinical hypothyroidism thyroid hormone therapy should be recommended more often with respect to analysis of effectiveness and risks. There is no cost-difference between treated patients and those who undergo thyroid hormone controls only, but thyroid hormone therapy probably induces improvement of clinical and laboratory parameters and reduction of cardiovascular risk factors. These therapeutic effects have to be elucidated in clinical prospective studies. Thyroid hormone therapy of patients with autoimmune thyroiditis and still euthyroid function obviously inhibits the autoimmune process and development of hypothyroidism. A final recommendation, however, can be given after the data of clinical studies with larger populations are available.

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Year:  2003        PMID: 12914400     DOI: 10.1007/s00108-003-0875-y

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  22 in total

1.  Reversible increase of intraocular pressure in subclinical hypothyroid patients.

Authors:  M Centanni; R Cesareo; O Verallo; M Brinelli; G Canettieri; N Viceconti; M Andreoli
Journal:  Eur J Endocrinol       Date:  1997-06       Impact factor: 6.664

2.  One-year prophylactic treatment of euthyroid Hashimoto's thyroiditis patients with levothyroxine: is there a benefit?

Authors:  S Padberg; K Heller; K H Usadel; P M Schumm-Draeger
Journal:  Thyroid       Date:  2001-03       Impact factor: 6.568

Review 3.  Hypothyroidism: screening and subclinical disease.

Authors:  A P Weetman
Journal:  BMJ       Date:  1997-04-19

4.  Does treatment with L-thyroxine influence health status in middle-aged and older adults with subclinical hypothyroidism?

Authors:  R Jaeschke; G Guyatt; H Gerstein; C Patterson; W Molloy; D Cook; S Harper; L Griffith; R Carbotte
Journal:  J Gen Intern Med       Date:  1996-12       Impact factor: 5.128

5.  A double-blind cross-over 12-month study of L-thyroxine treatment of women with 'subclinical' hypothyroidism.

Authors:  E Nyström; K Caidahl; G Fager; C Wikkelsö; P A Lundberg; G Lindstedt
Journal:  Clin Endocrinol (Oxf)       Date:  1988-07       Impact factor: 3.478

6.  Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study.

Authors:  A E Hak; H A Pols; T J Visser; H A Drexhage; A Hofman; J C Witteman
Journal:  Ann Intern Med       Date:  2000-02-15       Impact factor: 25.391

7.  Spectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissues.

Authors:  J J Staub; B U Althaus; H Engler; A S Ryff; P Trabucco; K Marquardt; D Burckhardt; J Girard; B D Weintraub
Journal:  Am J Med       Date:  1992-06       Impact factor: 4.965

8.  L-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial.

Authors:  D S Cooper; R Halpern; L C Wood; A A Levin; E C Ridgway
Journal:  Ann Intern Med       Date:  1984-07       Impact factor: 25.391

9.  Prevalence and correction of hypothyroidism in a large cohort of patients referred for dyslipidemia.

Authors:  T Diekman; P J Lansberg; J J Kastelein; W M Wiersinga
Journal:  Arch Intern Med       Date:  1995-07-24

10.  Subclinical hypothyroidism: neurobehavioral features and beneficial effect of L-thyroxine treatment.

Authors:  F Monzani; P Del Guerra; N Caraccio; C A Pruneti; E Pucci; M Luisi; L Baschieri
Journal:  Clin Investig       Date:  1993-05
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