Literature DB >> 12914130

Secondary rifampin resistance following multi-drug therapy--a case report.

Gift Norman1, Geetha Joseph, Gigi Ebenezer, Sundar P Rao, Charles K Job.   

Abstract

This is the first report of secondary resistance to rifampin following MDT in a patient with prolonged, but irregular treatment. Repeated mouse foot-pad studies demonstrated resistance to dapsone after several years of monotherapy, and following subsequent MDT the studies demonstrated the development of resistance to rifampin.

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Year:  2003        PMID： 12914130     DOI： 10.1489/1544-581x(2003)71<18:srrfmt>2.0.co;2

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN： 0148-916X


  4 in total

1.  Comparative modeling of UDP-N-acetylmuramoyl-glycyl-D-glutamate-2, 6-diaminopimelate ligase from Mycobacterium leprae and analysis of its binding features through molecular docking studies.

Authors:  Anusuya Shanmugam; Jeyakumar Natarajan
Journal:  J Mol Model       Date:  2011-04-15       Impact factor: 1.810

2.  Amino acid substitutions at position 95 in GyrA can add fluoroquinolone resistance to Mycobacterium leprae.

Authors:  Kazumasa Yokoyama; Hyun Kim; Tetsu Mukai; Masanori Matsuoka; Chie Nakajima; Yasuhiko Suzuki
Journal:  Antimicrob Agents Chemother       Date:  2011-11-21       Impact factor: 5.191

3.  Homology modeling and docking analyses of M. leprae Mur ligases reveals the common binding residues for structure based drug designing to eradicate leprosy.

Authors:  Anusuya Shanmugam; Jeyakumar Natarajan
Journal:  J Mol Model       Date:  2011-11-19       Impact factor: 1.810

Review 4.  Treatment and Evaluation Advances in Leprosy Neuropathy.

Authors:  Gigi J Ebenezer; David M Scollard
Journal:  Neurotherapeutics       Date:  2021-11-19       Impact factor: 7.620
  4 in total

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