Literature DB >> 12913248

Polyhydroxylated steroids and other constituents of the soft coral Nephthea chabroli.

Weihan Zhang1, Wing Keung Liu, Chun-Tao Che.   

Abstract

Polyhydroxylated steroids and other metabolites were isolated from the soft coral Nephthea chabroli collected in South China Sea. The structures of two new compounds were determined to be 24-methylcholesta-9(11), 24(28)-diene-3beta,12alpha,19-triol and 4alpha-methyl-3beta,14beta-dihydroxy-5alpha-ergost-24(28)-en-23-one on the basis of spectroscopic analysis. Cytotoxic activities of the polyhydroxylated sterols were evaluated on prostate carcinoma LNCaP cell line.

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Year:  2003        PMID: 12913248     DOI: 10.1248/cpb.51.1009

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

1.  Cytotoxic, cytostatic and HIV-1 PR inhibitory activities of the soft coral Litophyton arboreum.

Authors:  Mona S Ellithey; Namrita Lall; Ahmed A Hussein; Debra Meyer
Journal:  Mar Drugs       Date:  2013-12-10       Impact factor: 5.118

2.  A new 4alpha-methylated sterol from a Nephthea sp. (Nephtheidae) Bornean soft coral.

Authors:  Takahiro Ishii; Hiroshi Matsuura; Zhan Zhaoqi; Charles Santhanaraju Vairappan
Journal:  Molecules       Date:  2009-09-02       Impact factor: 4.411

  2 in total

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